Myasthenia gravis and alopecia areata

Abstract

Of 202 patients with myasthenia gravis (MG), 6 (3%) developed alopecia areata. All six patients had a thymoma verified by pathology; the frequency of alopecia areata rose to 17% of 35 MG patients with a thymoma. In one patient who had no recognizable tumor in the mediastinum, an ectopic thymoma was present in the anterior neck.

Frequency and clinical correlates of vitiligo in myasthenia gravis

“…This result contrasts with the other skin disorders accompanying MG, pemphigus and alopecia areata, which have an apparent relationship with MG and thymoma [3]. We present a case of paroxysmal hemiballism in a patient with hypoparathyroidism and extensive calcification of basal ganglia, in whom two episodes of hemiballism were associated with pronounced hypocalcaemia, whose correction was followed with complete resolution of the involuntary movements within 2-3 h. A female patient, aged 48 years, was hospitalized 15 years previously because of three episodes of tonicclonic seizures, associated with painful muscle cramps.…”

Multiple paraneoplastic syndromes: Myasthenia gravis, vitiligo, alopecia areata, and oral lichen planus associated with thymoma

“…There is general agreement that alopecia areata is an autoimmune disease. Alopecia areata is found at an increased frequency in thymoma patients with myasthenia gravis [10,11,[13][14][15].…”

A Case of Isolated Plexiform Neurofibroma in a Patient with Myasthenia Gravis

“…It may cause double vision, drooping eyelids, difficulties with speech, chewing, swallowing and breathing, as well as limb weakness. Myasthenia gravis is associated with other autoimmune diseases, such as thyroiditis, rheumatoid arthritis, systemic lupus erythematosus and thymoma 3,13 . It is also associated with skin diseases such as pemphigus, alopecia areata, vitiligo and psoriasis 3-,5,14 .…”

“…However, a few cases of isolated plexiform neurofibroma that were not associated with NF1 have been reported. Myasthenia gravis is a relatively rare autoimmune disorder of the peripheral nerves associated with pemphigus, alopecia areata and psoriasis [3][4][5] . The development of an isolated plexiform neurofibroma in myasthenia gravis has not been reported.…”