Myasthenic crisis-like syndrome due to &lt;i&gt;Cleistanthus collinus&lt;/i&gt; poisoning

Vengamma, B; Rao, MH; Damodaram, P; Manohar, I Chiranjeevi; Kumar, D Prabath

doi:10.4103/0019-5359.39368

Cited by 8 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various clinical manifestations of C. collinus poisoning in humans are listed in Table 1. 6,20,21 Comparison of clinical profile of patients with C. collinus poisoning in some of the published studies from India, as shown in Table 2.…”

Section: Clinical Presentationmentioning

confidence: 99%

Cleistanthus collinus Poisoning

Harikrishna

2019

Indian Journal of Critical Care Medicine

Self Cite

View full text Add to dashboard Cite

Section: Clinical Presentationmentioning

confidence: 99%

Cleistanthus collinus Poisoning

Harikrishna

2019

Indian Journal of Critical Care Medicine

Self Cite

View full text Add to dashboard Cite

Cleistanthin A causes peripheral vasoconstriction and myocardial depression in isolated tissue preparations

Padmaja,

Parameswaran,

Srisangeetha

et al. 2023

Toxicology Mechanisms and Methods

View full text Add to dashboard Cite

Epidemiology ofCleistanthus collinus(oduvan) poisoning: clinical features and risk factors for mortality

Shankar

Jose

Bangdiwala

et al. 2009

International Journal of Injury Control and Safety Promotion

View full text Add to dashboard Cite

Cleistanthus collinus (local name: oduvan) poisoning is a common suicidal poisoning method used in rural southern India. There are few studies on this issue and they have small sample sizes. This study examines the epidemiology of oduvan poisoning in a large sample, highlighting socio-demographic and clinical profile, complications, and risk factors for mortality. This study is a retrospective case series of 127 oduvan intentionally poisoned patients presenting at a tertiary care teaching hospital between the years 1990-1999. Descriptive statistics, cumulative case fatality rates and time to death from ingestion of poison were calculated. Cox regression adjusting for left truncation was used to investigate the effects of covariates on death. Patients' average (sd) age was 29.1 (10.9), 62% were female, 76% were married and 49% were housewives. The cumulative case fatality rate was 30%. The median time to death after oduvan ingestion was 3 days. Common signs and symptoms included hypokalaemia, vomiting, hyponatraemia, altered sensorium, bradycardia and abnormal ECG. There was a 58% risk reduction (95% CI: 29-75) in death with each 1 mmol/l increase in plasma potassium level. Patient's age was associated with an increased risk of death and the estimated hazard ratio for an increase of 10 years in age was 1.56 (95% CI: 1.18-2.07). Use of boiled oduvan extract was associated with an increased mortality (HR: 2.71, 95% CI: 1.17-6.32) compared to ingesting fresh leaves. Risk factors for oduvan poisoning mortality were hypokalaemia, older age, mode of consumption and an elevated risk for death with presence of chronic disease. When consumed as a boiled extract, oduvan is more lethal. We recommend close monitoring, correction of plasma potassium and appropriate supportive measures.

show abstract

Myasthenic crisis-like syndrome due to <i>Cleistanthus collinus</i> poisoning

Cited by 8 publications

References 5 publications

Cleistanthus collinus Poisoning

Cleistanthus collinus Poisoning

Cleistanthin A causes peripheral vasoconstriction and myocardial depression in isolated tissue preparations

Epidemiology ofCleistanthus collinus(oduvan) poisoning: clinical features and risk factors for mortality

Contact Info

Product

Resources

About