Mycétome actinomycosique du pied à Actinomycetes viscosus au Maroc

Baha, H.; Khadir, K.; Hali, F.; Benchikhi, H.; Zeghwagh, A.; Zerouali, Khalid; Belabbes, H.; Mdaghri, N. El; Soussi, M; Marnissi, F.; Kadioui, F. El

doi:10.1016/j.mycmed.2014.10.025

Cited by 4 publications

(8 citation statements)

References 16 publications

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“…The long course of the disease and its extension to adjacent structures may also play a role in the misdiagnosis of malignancies. Recently, in Morocco, another case has been reported where the patient had been misdiagnosed as Kaposi’s sarcoma, and given chemotherapy before the correct diagnosis of mycetoma [ 18 ]. Typically, our case illustrated also the diagnostic challenge posed by mycetoma especially in non endemic areas.…”

Section: Discussionmentioning

confidence: 99%

“…With HES stain, the grains represent colonies of the causative agent, surrounded by granulomatous inflammation composed of plasma cells, polymorphonuclear cells, macrophages and giant cells. Colonies from actinomycetoma have different size, often round or multilobulated, with deeply stained basophilic outer border and slightly paler center [ 14 , 15 , 18 ]. Sometimes, an eosinophilic hyaline-like material surrounds the colonies, this aspect is referred to as Splendore-Hoeppli Phenomenon [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

“…Actinomycetoma is treated by a combination of trimethoprim and sulfamethoxazole with aminosids (amikacin or netilmicine), for weeks. The prognosis of actinomycetoma seems to be better compared to eumycetoma [ 1 , 6 , 18 ]. Table 1 summarizes some different charactristics of eumycetoma and actinomycetoma.…”

Section: Discussionmentioning

confidence: 99%

“…Despite the long-term treatment and recurrences observed in medical treatment, aggressive surgery is not the first line of treatment [ 1 , 6 , 19 ]. Amputations are generally due to misdiagnosis or a long-standing disease that spreads to deeper structures of the body [ 5 , 7 , 11 , 18 ]. In fact, our patient should have been treated medically, rather than surgically, but the misdiagnosis due to the fact that clinicians were not familiar to mycetoma here in Morocco, as it is not an endemic area of mycetoma.…”

Section: Discussionmentioning

confidence: 99%

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Mycetoma in a non-endemic area: a diagnostic challenge

et al. 2017

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BackgroundMycetoma is a chronic granulomatous infectious disease caused by filamentous bacteria or by fungi. The disease is endemic in certain tropical and subtropical areas of the world but can be found elsewhere posing sometimes a diagnostic challenge for clinicians.Case presentationA 65-year- old man presented with a right foot swelling evolving for 25 years. During that time, several diagnosis and treatments have been made without any improvement. The disease spread to bones, and misdiagnosed as Kaposi’s sarcoma. Transtibial amputation has been performed, and the histopathological examination revealed finally the diagnosis of eumycotic mycetoma. The patient recovered well after surgery and orthopedic prosthesis was prescribed for him.ConclusionMycetoma in non endemic areas is usually misdiagnosed and mismanaged leading to unnecessary and inappropriate surgery. Health practitioners should be aware of that fact in order to provide an accurate management.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Mycetoma in a non-endemic area: a diagnostic challenge

et al. 2017

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“…Mycetoma infection are rare in Morocco, commonly found in tropical and temperate countries [1]. They are secondary to bacterial agents (actinomycosis) or fungal agents (eumycetomes), both types give the same clinical presentation [2].…”

Section: Discussionmentioning

confidence: 99%

Mycetoma of midfoot: A Moroccan case

Mohsine¹,

Zineb²,

Hanane³

et al. 2016

SJMCR

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Actinomycosis or mycetoma is an infectious process caused by a fungal or bacterial agent, giving a pseudotumoral appearance. The evolution is insidious; the bone location at the foot of the far more common; bone disease is a complication that increases the therapeutic management. We report the case of an adult male of 40 years, admitted to swelling of the midfoot, and in histological examination confirmed actinomycosis. Medically treated by antibiotherapy with a favorable outcome. The aim of this work is to recall this affection often unrecognized by rheumatologists so the therapeutic modalities.

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Estimated Incidence and Prevalence of Serious Fungal Infections in Morocco

Lmimouni

Hennequin

Penney³

et al. 2022

JoF

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Few data are published from Morocco on fungal disease, although numerous case reports attest to a wide range of conditions in the country. Here, we estimate for the first time the incidence and prevalence of serious fungal diseases in the country. Detailed literature searches in English and French were conducted for all serious fungal infections. Demographic and individual underlying condition prevalence or annual incidence were obtained from UNAIDS (HIV), WHO (TB) and other international sources. Deterministic modelling was then applied to estimate fungal disease burden. Morocco’s population in 2021 was 36,561,800. Multiple publications describe various fungal diseases, but epidemiological studies are rare. The most frequent serious fungal infections were tinea capitis (7258/100,000) and recurrent vulvovaginal candidiasis (2794/100,000 females). Chronic pulmonary aspergillosis is also common at a prevalence of 19,290 (53/100,000) because of the relatively high rate of tuberculosis. The prevalence of asthma in adults exceeds one million, of whom fungal asthma (including allergic bronchopulmonary aspergillosis (ABPA)) probably affects 42,150 (115/100,000). Data are scant on candidaemia (estimated at 5/100,000), invasive aspergillosis (estimated at 4.1/100,000), HIV-related complications such as cryptococcal meningitis and Pneumocystis pneumonia and mucormycosis. Fungal keratitis is estimated at 14/100,000). Mycetoma and chromoblastomycosis are probably rare. Fungal disease is probably common in Morocco and diagnostic capacity is good in the teaching hospitals. These estimates need confirmation with methodologically robust epidemiological studies.

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Mycétome actinomycosique du pied à Actinomycetes viscosus au Maroc

Cited by 4 publications

References 16 publications

Mycetoma in a non-endemic area: a diagnostic challenge

Mycetoma in a non-endemic area: a diagnostic challenge

Mycetoma of midfoot: A Moroccan case

Estimated Incidence and Prevalence of Serious Fungal Infections in Morocco

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