2024
DOI: 10.3390/ijms25147771
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Mycobacterial Biofilm: Mechanisms, Clinical Problems, and Treatments

Xining Liu,
Junxing Hu,
Wenzhen Wang
et al.

Abstract: Tuberculosis (TB) remains a threat to human health worldwide. Mycobacterium tuberculosis (Mtb) and other nontuberculous mycobacteria (NTM) can form biofilms, and in vitro and animal experiments have shown that biofilms cause serious drug resistance and mycobacterial persistence. Deeper investigations into the mechanisms of mycobacterial biofilm formation and, consequently, the exploration of appropriate antibiofilm treatments to improve the efficiency of current anti-TB drugs will be useful for curing TB. In t… Show more

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