Mycobacterial Skin Infections

Sethuraman, Gomathy; Dev, Tanvi; Ramesh, V.

doi:10.1002/9781119142812.ch42

Cited by 2 publications

(2 citation statements)

References 73 publications

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“…On the head and neck, four cases of lupus vulgaris were detected, two on the neck, one on the cheek and the other in the infra-auricular area. Bhambani et al 23 and Savin et al 24 discovered that 40% and 80% of the cases of lupus vulgaris were on the face, respectively in their studies. In the study carried out by Sabir et al, 25 the average age of presentation was 22 years, and four out of nine cases of lupus vulgaris were on the face.…”

Section: Discussionmentioning

confidence: 96%

Histopathological spectrum of skin lesions in a tertiary health care centre – A retrospective study

Mahapatra,

Das,

Mishra

et al. 2024

PJMS

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Skin is the body’s largest and most complex organ, performing a wide range of functions. Environmental factors, genetics, cleanliness standards and social norms all influence the type of skin lesions that exist in different countries and regions. The skin lesions can vary from inflammatory to neoplastic. In clinically alike dermatoses, skin biopsy is used to provide significant information to the pathologist and dermatologist. The aim of the study is to identify and discuss the histopathology of different types of skin lesions, as well as their prevalence, age, sex distribution and location of lesions among hospital patients and compare the results with other relevant studies. The study was a retrospective observational study undertaken for the duration of three years in the Pathology Department of a tertiary health care center. Skin biopsy slides stained with hematoxylin and eosin were studied and classified after a detailed histopathological study under light microscope. 178 cases of skin lesions in total were evaluated having a 1.5:1 male to female ratio. Nonneoplastic lesions constituted 30.33% of skin lesions, while benign and malignant tumors constituted 55.05% and 14.6% of skin lesions respectively. In neoplastic lesions, keratinocytic tumors were the most common tumor type. The most common malignant tumor was squamous cell carcinoma, whereas epidermal inclusion cyst was the most prevalent benign tumor. The head and neck were the most prevalent sites for skin lesions. Most of the skin lesions can be accurately diagnosed by histopathological evaluation of biopsy of lesions in combination with clinical findings.

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Section: Discussionmentioning

confidence: 96%

Histopathological spectrum of skin lesions in a tertiary health care centre – A retrospective study

Mahapatra,

Das,

Mishra

et al. 2024

PJMS

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“…They possess waxy cell wall composed of mycolic acid, enabling them to be resistant to decolorization even with the use of acidified alcohol. The acid-fastness property of mycobacteria can be demonstrated by the Ziehl-Neelsen stain [1] . In general, the genus Mycobacterium is broadly categorized into three main groups which include the Mycobacterium tuberculosis complex (MTC), Mycobacterium leprae and non-tuberculous mycobacteria (NTM).…”

Section: Introductionmentioning

confidence: 99%

Mycobacterium ulcerans and Mycobacterium marinum: Pathogenesis, Diagnosis and Treatment

Tan¹,

Raghunath²,

Ming³

et al. 2020

Prog Micobes Mol Biol

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Skin and soft tissue infections are common presentations for non-tuberculous mycobacteria (NTM). The cutaneous infections caused by NTM may cause localized or diffuse lesions. M. ulcerans is one of the most identified pathogens that involves in the skin and soft tissue mycobacterial infections. Meanwhile, M. marinum, as an NTM has also become important emerging causal agents of cutaneous disease in various geographical regions. Although having common ancestry and highly similar in genetic makeup, M. ulcerans and M. marinum have differential impacts on the host innate immune system. In term pathogenesis, prolonged cell exposure to exotoxin mycolactone produced by M. ulcerans could lead to Buruli ulcer. Meanwhile, like most pathogenic mycobacteria, M. marinum evades the host immune responses by invading and replicating inside host cells and it is capable of modulating host immune responses. This article aims to provide a general overview and comparisons between the pathogenesis, diagnosis, prevention and therapeutic strategies for M. ulcerans and M. marinum.

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Mycobacterial Skin Infections

Cited by 2 publications

References 73 publications

Histopathological spectrum of skin lesions in a tertiary health care centre – A retrospective study

Histopathological spectrum of skin lesions in a tertiary health care centre – A retrospective study

Mycobacterium ulcerans and Mycobacterium marinum: Pathogenesis, Diagnosis and Treatment

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