Mycobacterium avium complex spinal epidural abscess in an HIV patient

Rotstein, Andrew; Stuckey, Stephen

doi:10.1046/j.1440-1673.1999.00732.x

Cited by 13 publications

(9 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As in the cat described here, the most common finding on spinal MRI of people with tuberculous meningitis is meningeal enhancement; however, the presence of a tuberculoma is rare 16 . Most cases of tuberculosis affecting the epidural space in people are attributed to M. tuberculosis (or MAC) rather than M. microti infection 13–15,18 ; although one case of M. microti infection also involving the vertebral body has been described 17 …”

Section: Discussionmentioning

confidence: 72%

See 1 more Smart Citation

Clinical resolution of systemic mycobacterial infection in a cat with a suspected spinal granuloma

Francés

Pradel

Domínguez

et al. 2023

Vet Record Case Reports

View full text Add to dashboard Cite

An 8‐year‐old, female, spayed, domestic longhair cat presented with progressive pelvic limb weakness, lethargy and weight loss. Physical examination identified bilateral pelvic limb proprioceptive ataxia, tachypnoea and a subcutaneous nodular lesion on the left flank. Investigations documented a diffuse broncho‐interstitial and nodular pulmonary pattern, pyogranulomatous inflammation in the spleen and an intradural‐extramedullary spinal lesion at the level of L3. Mycobacterium microti was confirmed based on demonstration of organisms on histopathology of the subcutaneous nodule using Ziehl–Neelsen stain together with positive polymerase chain reaction and interferon‐gamma release assay results. Therapy with rifampicin, azithromycin and pradofloxacin was administered for 7 months. Serial monitoring, including repeated magnetic resonance imaging, demonstrated resolution of the clinical signs, pulmonary, subcutaneous and spinal lesions.

show abstract

Section: Discussionmentioning

confidence: 72%

“…Spinal tuberculosis has been well described in people, and typically presents as spondylitis or diskospondylitis, occasionally affecting the meninges, spinal cord and spinal nerve roots to varying frequency 12–18 . However, there is a paucity of publications reporting tubercular intradural lesions without osseous involvement 13–16 .…”

Section: Discussionmentioning

confidence: 99%

Clinical resolution of systemic mycobacterial infection in a cat with a suspected spinal granuloma

Francés

Pradel

Domínguez

et al. 2023

Vet Record Case Reports

View full text Add to dashboard Cite

show abstract

“…MAC consists of two phenotypically similar organisms, M. avium and M. intracellulare. The organisms are quite ubiquitous in nature being found in water, soil and food and can be acquired via inhalation or ingestion [4] . Initially a common opportunistic infection in patients with AIDS, this diagnosis has become less frequent with widespread use of combination antiretroviral therapy.…”

Section: Discussionmentioning

confidence: 99%

Mycobacterium avium–intracellulare brain abscesses in an HIV-infected patient

Begley

Amaraneni

Lutwick

2015

IDCases

View full text Add to dashboard Cite

The Mycobacterium avium–intracellulare complex (MAC) is an uncommon cause of brain abscesses even in patients with acquired immunodeficiency syndrome (AIDS). We present a case of a multiple MAC brain abscesses, confirmed by brain biopsy and culture, in a patient with AIDS. The patient's initial symptoms were weakness, confusion and headaches. The patient was initially treated for toxoplasmosis and pyogenic bacterial brain abscesses with no resolution. Following treatment for MAC the patient's abscesses resolved.

show abstract

“…In the current literature, we could find no cervical epidural abscess caused by Enterococcus species. However, it is not unusual to culture relatively uncommon pathogens in patients with multiple comorbidities and/or immunological deficiencies [15–17]. …”

Section: Discussionmentioning

confidence: 99%

Insidious Onset of Tetraparesis due to Cervical Epidural Abscess fromEnterococcus faecalis

Soultanis

Sakellariou

Starantzis

et al. 2013

Case Reports in Medicine

View full text Add to dashboard Cite

We report a case of cervical epidural abscess from Enterococcus faecalis, which caused an insidious onset of tetraparesis. This 53-year-old female with a history of diabetes mellitus and chronic renal failure under hemodialysis presented with pain and progressive weakness of upper and lower extremities without fever. Although a recent MRI she did at the beginning of symptoms showed no significant pathologies, except for a cervical disc herniation and adjacent spinal degeneration, and stenosis that confused the diagnostic procedure, newer imaging with CT and MRI, which was performed due to progression of tetraparesis, revealed the formation of a cervical epidural abscess. Surgical drainage was done after a complete infection workup. The patient showed immediate neurological improvement after surgery. She received antibiotics intravenously for 3 weeks and orally for another 6 weeks. The patient was free from complications 24 months after surgery. A high index of suspicion is most important in making a rapid and correct diagnosis of spinal epidural abscess. The classic clinical triad (fever, local pain, and neurologic deficits) is not sensitive enough for early detection. Continuous clinical, laboratory, and imaging monitoring are of paramount importance. Early diagnosis and surgical intervention could optimize the final functional outcome.

show abstract

Mycobacterium avium complex spinal epidural abscess in an HIV patient

Cited by 13 publications

References 15 publications

Clinical resolution of systemic mycobacterial infection in a cat with a suspected spinal granuloma

Clinical resolution of systemic mycobacterial infection in a cat with a suspected spinal granuloma

Mycobacterium avium–intracellulare brain abscesses in an HIV-infected patient

Insidious Onset of Tetraparesis due to Cervical Epidural Abscess fromEnterococcus faecalis

Contact Info

Product

Resources

About