Mycobacterium tuberculosis transmission among high school students in Greece

Hadjichristodoulou, Christos; VAsilogiannakopoulos, Antonis; Spala, G; Mavrou, Irini; Kolonia, Virginia; Marinis, E.; Syriopoulou, Vasiliki; Theodoridou, Maria

doi:10.1111/j.1442-200x.2005.02044.x

Pediatrics International

2005

DOI: 10.1111/j.1442-200x.2005.02044.x

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Mycobacterium tuberculosis transmission among high school students in Greece

Christos Hadjichristodoulou¹,

Antonis VAsilogiannakopoulos²,

G Spala³

et al.

Abstract: There was a considerable difference in the infectivity of the two cases presumably due to environmental and clinical factors, although two different MTB strains were responsible. It is proposed that the extent of case investigation should be individualized with particular emphasis placed among close contacts.

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The impact on community acquired pneumonia empirical therapy of diagnostic bronchoscopic techniques

Manali¹,

Παπαδοπουλοσ²,

Tsiodras³

et al. 2008

Scandinavian Journal of Infectious Diseases

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The aim of the present study was to examine the modification of initial empirical treatment based on the microbiological results of bronchoscopic techniques after comparing the diagnostic yield of protected specimen brush (PSB) and bronchoalveolar lavage (BAL) in the immunocompetent patient with community acquired pneumonia (CAP) with results obtained from conventional sputum cultures. 88 patients with presumptive diagnosis of CAP necessitating hospitalization were prospectively studied. Fibreoptic bronchoscopy with quantitative PSB and BAL cultures for common pathogens, mycobacteria and fungi was performed. Conventional sputum cultures were also obtained. PSB and BAL quantitative cultures added 26.1% and 36.4%, respectively, more microbiological documentation for CAP compared to conventional sputum cultures (p < 0.0001). Gram staining was indicative of the pathogen mostly in cases where Streptococcus pneumoniae was isolated, which was also the most frequently isolated pathogen (19.3%), followed by Haemophilus influenzae (9%). M. tuberculosis was isolated in 6.8% of patients. Modification of treatment ensued in 27.3% of patients because of the application of the cultures of sputum and invasive technique. PSB and BAL added significant information to the aetiological diagnosis of hospitalized immunocompetent patients with CAP.

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The impact on community acquired pneumonia empirical therapy of diagnostic bronchoscopic techniques

Manali¹,

Παπαδοπουλοσ²,

Tsiodras³

et al. 2008

Scandinavian Journal of Infectious Diseases

View full text Add to dashboard Cite

show abstract

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Mycobacterium tuberculosis transmission among high school students in Greece

Cited by 1 publication

References 16 publications

The impact on community acquired pneumonia empirical therapy of diagnostic bronchoscopic techniques

The impact on community acquired pneumonia empirical therapy of diagnostic bronchoscopic techniques

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