Mycoplasma host specificity: Fact or fiction?

Pitcher, D.G.; Nicholas, R. A. J.

doi:10.1016/j.tvjl.2004.08.011

Cited by 88 publications

(64 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hemoplasma infections may occur more frequently than is generally recognized, given that these organisms fail to grow in culture and only a few laboratories are equipped to detect and identify hemoplasmas (1). Disease associations with latent mycoplasma infections in immunocompromised and nonimmunocompromised patients are now emerging.…”

Section: Discussionmentioning

confidence: 99%

“…are host specifi c. However, there are occasional reports of infection in an animal species not perceived as primary hosts. These infections may have a pathologic effect, particularly when predisposing conditions, such as immunodefi ciency, are present (1). We report a case of Mycoplasma haemofelislike infection in an HIV-positive patient with disseminated Bartonella henselae infection.…”

mentioning

confidence: 91%

See 1 more Smart Citation

HemoplasmaInfection in HIV-positive Patient, Brazil

Santos¹,

Santos²,

Biondo³

et al. 2008

Emerg. Infect. Dis.

137
1
66
0

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning
confidence: 99%

mentioning
confidence: 91%

HemoplasmaInfection in HIV-positive Patient, Brazil
Santos¹,
Santos²,
Biondo³
et al. 2008
Emerg. Infect. Dis.
137
1
66
0
View full text Add to dashboard Cite

show abstract

“…By definition, the Mycoplasma genus contains the bacterial species that are sensitive to digitonin and are restricted to vertebrate animal hosts (Quinn et al, 2011). Organisms within the Mycoplasma genus are often portrayed as the simplest self-replicating life forms due to their minute size, total lack of a cell wall, paucity of metabolic pathways meaning that they are often dependent on host cells for much of their nutritional requirements; and a reduced genome size which has a low guanine (G) and cytosine (C) content (Bove, 1993, Chazel et al, 2010, Citti et al, 2010, Miles and Nicholas, 1998, Pitcher and Nicholas, 2005.…”

Section: Taxonomic Classificationmentioning
confidence: 99%

“…Despite most mycoplasmas often regarded as highly adapted to a specific host species, isolations of M. bovis from animals other than the bovine have been reported. Studies have isolated M. bovis from goats, chickens, humans and pigs, but often in these situations there is an association with another underlying condition (Bashiruddin et al, 2005, Ongor et al, 2008, Pitcher and Nicholas, 2005, Spergser et al, 2013. In other cases, M. bovis has been isolated as the sole pathogen.…”

Section: Host Specificitymentioning
confidence: 99%

“…Indirect transmission is possible through ingestion of contaminated milk, feed or water, or contact with contaminated bedding or fomites (Maunsell et al, 2011). Additional sources of infectious material are mucosal surface secretions from the teat canal or genital tract of adult cattle, as well as contaminated frozen semen , Nicholas and Ayling, 2003, Pitcher and Nicholas, 2005, Sachse et al, 2010.…”

Section: Reservoir and Transmissionmentioning
confidence: 99%

See 1 more Smart Citation
Mycoplasma bovis in Australian feeder cattle
Schibrowski¹
0
0
0
0
View full text Add to dashboard Cite
Mycoplasma bovis can be a commensal bacterial inhabitant of the upper respiratory tract of healthy bovines. However, under certain circumstances and conditions that are incompletely understood, M. bovis can be associated with a number of clinical syndromes, one of which is bovine respiratory disease (BRD). In Australia, there is little information on the prevalence and epidemiology M. bovis in beef production systems. The overall aim of this thesis was to help close this knowledge gap.Commercially available serological diagnostic methods for the detection of M. bovis-specific antibody have not been validated in the Australian cattle population. Arguably, more importantly, however is the fact that diagnostic sensitivity (Se) and specificity (Sp) and / or analytical sensitivity (ASe) and specificity (ASp) estimates for commercially available M. bovis sero-diagnostic tests are not available. 28% (95% CI: 1% -92%). However, in terms of Sp the commercial ELISAs out performed western blotting; BioK302: 96% (95% CI: 87% -99%); BioK260:100% (95% CI: 93% -100%) and western blotting: 88% (95% CI: 56% -98%) respectively. In terms of both Se and Sp combined, none of the methods assessed here performed well. As such, when interpreting the results obtained from these ELISAs, the potential impact imperfect Se and / or Sp can have needs to be considered.Despite the poor performance of the BioK302 and BioK260 ELISAs particularly in terms of Se, these tests were used to determine the sero-prevalence of M. bovis antibody in Australian feeder cattle at feedlot induction and draft (approximately 42 days on feed). Paired bovine sera from 1,354 randomly selected animals were sourced from a bovine serum bank (n = 35,160) collected as part of another study, The National Bovine Respiratory Disease Initiative. As the classification of the result of a single serum sample could differ between the BioK302 and BioK260, sero-prevalence estimates were obtained using the individual ELISA results in addition to series and parallel interpretation of the two ELISA kit results. The apparent sero-prevalence of M. bovis-specific antibody at feedlot induction estimates ranged from 2.4% -6.8% (95% CI: 1.3% -8.6%) and the apparent sero-prevalence estimates at draft ranged from 22.4% -44.2% (95% CI: 19.1% -48.6%). The level of sero-conversion to M. bovis between induction and draft was also determined. Only animals that were classified as sero-negative at induction were included in sero-conversion analyses. In the current study, 24.3% (95% iii CI: 20.8% -27.7%) and 19.5% (95% CI: 17.3% -21.7%) of animals sero-converted to M. bovis between induction and draft based on the BioK302 and dichotomised BioK260 ELISA results respectively.Using these ELISA results, an assessment of putative risk factors associated with sero-positivity at feedlot induction or sero-conversion between induction and draft was performed. An increased risk of sero-positivity at feedlot induction was found to be associated with; (i) history of exposure to a saleyard at least 27 d...
show abstract

Rats
2017
Pathology of Small Mammal Pets
1
0
0
0
View full text Add to dashboard Cite

Mycoplasma host specificity: Fact or fiction?

Cited by 88 publications

References 42 publications

HemoplasmaInfection in HIV-positive Patient, Brazil

HemoplasmaInfection in HIV-positive Patient, Brazil

Mycoplasma bovis in Australian feeder cattle

Rats

Contact Info

Product

Resources

About