Mycoplasma respiratory tract infection complicated by Stevens‐Johnson syndrome and surgical emphysema

Amin, Rakesh; Smit, Elisa; Shaikh, Guftar; Rawling, Philippa; Alexander, Eliza

doi:10.1111/j.1651-2227.2007.00088.x

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…O risco de desenvolver NTE é, ainda, 1000 vezes superior nos doentes infectados pelo Vírus da Imunodeficiência Humana 5,11,12 . Subsidiariamente, também foram implicados como agentes causais destas toxidermias, a exposição solar, aditivos alimentares, fumigantes e outros químicos domésticos 16 e, mais raramente, infecções, designadamente infecções por Mycoplasma peumoniae 17 .…”

Section: Introductionunclassified

Síndroma de Stevens-Johnson e necrólise tóxica epidérmica: um estudo retrospectivo de 15 anos.

Moniz

Casal²,

Mavioso³

et al. 2011

Acta Med Port

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Stevens-Johnson Syndrome (SJS), Overlap Syndrome (OS) and Toxic Epidermal Necrosis (TEN) are rare medical emergencies associated with a high morbidity and mortality. The literature on the characteristics of these diseases in Portugal is scarce. A retrospective study was conducted based on the clinical notes of the 20 patients admitted to São José Burn Unit in the previous 15 years with the diagnosis of SJS, OS or TEN. Most patients had TEN (65%), followed by OS (25%) and SJS (10%). Average age was 57,1 ± 19,0 years. The mean duration of stay in the Burn Unit was 12,6 ± 7,8 days. Mortality was 50%, being significantly higher than the 16,4% overall mortality in the general Burn Unit population in the same period (p < 0,01). The mean surface area involved was 43,9 ± 28,6 %. Allopurinol was the causal agent most frequently implicated (35%) followed by UV light exposure (15%). Fourteen patients (70%) were treated with steroids in the first days, whereas six patients were treated conservatively (30%). Mortality was inferior in the patients treated with steroids (42,8 vs. 66,7%), even though this difference did not reach statistical significance. Infection rates were not significantly different between the two groups. SCORTEN score proved to be a good predictor of mortality. Further studies are needed to reduce mortality in these diseases.

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Section: Introductionunclassified

Síndroma de Stevens-Johnson e necrólise tóxica epidérmica: um estudo retrospectivo de 15 anos.

Moniz

Casal²,

Mavioso³

et al. 2011

Acta Med Port

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“…These air-leak syndromes are postulated to occur in the setting of alveolar rupture that results from air trapping due to the obstruction of airways by mucosal debris. Such complications are more frequently seen in pediatric patients, [37][38][39] possibly due to the occlusive effect on smaller airways.…”

Section: Acute Respiratory Complicationsmentioning

confidence: 99%

Managing respiratory complications in Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis

Lee

et al. 2021

Int J Dermatology

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In the recently published guidelines by the Society of Dermatology Hospitalists on the management of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), a brief section was included on airway management. These recommendations provide an easy reference on how to manage respiratory complications of the disease. Understanding the evidence that underlies these recommendations would offer physicians greater clarity on the considerations behind every decision and treatment offered. We present a review of the literature on respiratory manifestations associated with SJS and TEN. In addition, we aim to address specific concerns regarding the respiratory management of these patients.These include issues such as the indications and optimal timing of intubation, tracheostomy, role of flexible nasoendoscopy, bronchoscopy, ventilation strategies, and management of chronic respiratory complications.

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Mycoplasma pneumoniae–induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: A systematic review

Canavan

Mathes

Frieden

et al. 2015

Journal of the American Academy of Dermatology

283

421

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Mycoplasma respiratory tract infection complicated by Stevens‐Johnson syndrome and surgical emphysema

Cited by 5 publications

References 16 publications

Síndroma de Stevens-Johnson e necrólise tóxica epidérmica: um estudo retrospectivo de 15 anos.

Síndroma de Stevens-Johnson e necrólise tóxica epidérmica: um estudo retrospectivo de 15 anos.

Managing respiratory complications in Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis

Mycoplasma pneumoniae–induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: A systematic review

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