“…Although MF was first described in 1833 (Ahn et al, 2014) and our understanding of this disease continues to evolve, MF remains a significant diagnostic challenge (Arps et al, 2014, Diwan, 2016, Nashan et al, 2007, Ngan et al, 2014, Oschlies and Klapper, 2013) because it can have different diagnoses on the basis of clinical and histological test results, especially at the early stage of the infection (i.e., mainly inflammatory dermatoses). Despite advances in immunohistochemistry and molecular diagnostics, false-positive, false-negative, and indeterminate diagnoses are not uncommon.…”