Mycosis fungoides of the vulva

Abstract

Mycosis fungoides (MF) is an indolent form of non-Hodgkin lymphoma and the most common type of primary cutaneous T-cell lymphoma. The overall incidence of MF is approximately 4 per 1 million. Involvement of the vulva by MF is extremely rare, with only seven reported cases in the literature. At the vulva, it is mainly a metastatic lesion and rarely a primary malignancy. We describe a case of vulvar MF and discuss the previous cases. The presentation can easily be confused with benign skin disorders. A vulvar lesion can reflect a systemic disease. When a patient consults for a vulvar lesion it is therefore important not only to look at the vulva but also to examine her in and ask general questions. In a patient with a vulvar mass and cutaneous lesions on other locations MF should be considered in the differential diagnosis.

Proposal of a comprehensive model for palliative therapeutic interventions in patients with mycosis fungoides and Sézary syndrome

“…It is concerning that in this population, from an early stage like MF to SS, social stigmas can arise due to visible skin lesions, associated with the psychological or emotional issues of living with a chronic and potentially life-threatening disease, and often with financial difficulties and worsening symptoms associated with therapy [44][45][46] . Therefore, it is crucial to objectively evaluate interventions that can improve the quality of life of this population using various scales such as the Skindex-29 or the Skindex-16 to assess skin involvement, presence of pruritus, and severity quantification through a visual analog scale, depending on the targeted treatment 47,48 .…”

“…Modified Severity-Weighted Assessment Tool (mSWAT) 25,30 , Skindex-29/16 39 , Dermatology Life Quality Index (DLQI), Dermatology Life Quality Index 40 General tools for symptoms and specific perception Itchy Quality of Life (ItchyQoL) 41 , Pruritus ENA 42 , Pruritus-5D itch scale (5D) 43 , Revised Illness Perception Questionnaire (IPQ-R) 44 Cancer related Functional Assessment of Cancer Therapy (FACT-G), FACT-lym 36 , Spitzer 45 , Core Quality of Life Questionnaire (QLQ-C30) 46 Emotional symptoms Inventario de la dignidad del paciente 33 , Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) 47…”

Propuesta de modelo integral para intervenciones terapéuticas paliativas en pacientes con micosis fungoide y síndrome de Sézary

“…Por lo anterior, debemos valorar de manera objetiva las intervenciones que pueden mejorar la calidad de vida de esta población, con diferentes escalas, siendo útil la Skindex-29 o 16 para valorar el compromiso en la piel, la presencia de prurito y la cuantificación de la gravedad por una escala analógica visual, de acuerdo con el tratamiento dirigido en que se encuentre 47,48 .…”

“…Modified Severity-Weighted Assessment Tool (mSWAT) 25,30 , Skindex-29/16 39 , Dermatology Life Quality Index (DLQI), Dermatology Life Quality Index 40 Instrumentos genéricos para síntomas y percepciones específicas Itchy Quality of Life (ItchyQoL) 41 , Pruritus ENA 42 , Pruritus-5D itch scale (5D) 43 , Revised Illness Perception Questionnaire (IPQ-R) 44 Relacionadas con el cáncer Functional Assessment of Cancer Therapy (FACT-G), FACT-lym 36 , Spitzer 45 , Core Quality of Life Questionnaire (QLQ-C30) 46 Síntomas emocionales Inventario de la dignidad del paciente 33 , Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) 47 Síntomas asociados a disfunción sexual…”