Introduction: Mycotic aneurysms have an incidence of 1 to 2%. Before the era of antibiotics, syphilis was most commonly observed. However, with the increase in arterial interventional procedures and intravenous drug use, Gram-positive organisms such as Staphylococcus and Streptococcus are observed. Objectives: To analyze the clinical aspects and to evaluate the results of the surgery. Materials and Methods: This was a descriptive retrospective study over a 12-years period from December 2005 to February 2018. Results: The total number of our series was 12 cases. The average age at the time of surgery was 37 years old [17-83 years]. There was no predominance of sex. There was a notion of smoking in 3 cases / 12. There was no concept of addiction. Four out of 12 cases had a known concept of heart disease with mitral insufficiency, aortic insufficiency, and complete atrioventricular block. A patient presented in this antecedents a notion of syphilis treated and declared cured. The clinical symptomatology was made of fever in 4 cases out of 12, pain in 11 cases out of 12 with 3 cases of intermittent claudication. The clinical examination had shown a swelling with vascular characters in 11 cases out of 12. Two out of 12 patients had signs of acute limb ischemia. The arterial echodoppler was performed in 11cases out of 12 which had made the diagnosis. The angioscan was performed in 8 cases and showed 4 cases of sacciform aneurysms. All patients benefited from open surgery. The exploration showed 9 cases of false aneurysms with signs of local infection in 5 cases. Flattening with excision of the infected tissues was performed in all cases. The restoration of vascular continuity was immediate in all cases by end-to-end direct anastomosis in 8 cases, 2 cases of extra-anatomical bypass using a dacron tube and two cases of anatomical bypass using the saphenous vein in situ. Early complications were dominated by 2 cases of acute limb ischemia, 2 cases of superficial surgical site infection, 1 case of deep surgical site infection, 1 case of false aneurysm of a common femoral artery and 1 case of hematoma. Follow-up was performed in all patients with an average delay of 14 months [1-60]. There were 1 case of operative mortality and 2 cases of late mortality.