Mycotoxins in cereal grain. Part IV. Inactivation of ochratoxin A and other mycotoxins during ammoniation

Chełkowski, J.; Goliński, Piotr; Godlewska, B.; Radomyska, W.; Szebiotko, K.; Wiewiórowska, M.

doi:10.1002/food.19810250705

Cited by 40 publications

(23 citation statements)

References 4 publications

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“…Chelkowski and collaborators [79] reported that treatment of OTA-contaminated grain with ammonia reduced OTA concentrations to undetectable levels. Moreover, weight gains of chickens fed the OTA-contaminated grain were markedly decreased, whereas there was no reduction in weight gains when the chickens were fed the OTA-contaminated grain that had been ammoniated.…”

Section: Methods Of Prophylaxis and Various Preventive Measures Inmentioning

confidence: 99%

“…Moreover, weight gains of chickens fed the OTA-contaminated grain were markedly decreased, whereas there was no reduction in weight gains when the chickens were fed the OTA-contaminated grain that had been ammoniated. They concluded that ammoniation of grain not only detoxifies several mycotoxins, including OTA, but also inhibits mould growth [79]. Feeding studies have shown no toxic effects related to the ammoniation process, but there are some changes in the nutritional quality of the feed, such as a decrease in lysine and sulfur containing amino acids [80].…”

Section: Methods Of Prophylaxis and Various Preventive Measures Inmentioning

confidence: 99%

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Complex Etiology, Prophylaxis and Hygiene Control in Mycotoxic Nephropathies in Farm Animals and Humans

Stoev

2008

IJMS

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Abstract:Various etiological factors contributing to the development of mycotoxic nephropathy in farm animals and humans are reviewed. The possible synergistic effect between ochratoxin A (OTA) and other mycotoxins, as penicillic acid (PA) and fumonisin B 1 (FB 1 ), contributing to this nephropathy is also considered and discussed. The most convenient ways of prophylaxis and various preventive measures against OTA contamination of feeds or foods are reviewed. A reference is made concerning the most successful methods of veterinary hygiene control in the slaughterhouses in order to prevent the entering of OTA in commercial channels with a view to human health. The economic efficacy of these prophylactic procedures is also considered. An evaluation of human exposure to OTA is made.Keywords: mycotoxic nephropathy, Balkan endemic nephropathy, ochratoxin A, penicillic acid, fumonisin B 1 , synergism, preventive measures, hygiene control, pathogenesis Abbreviations: MN -mycotoxic nephropathy; MPN -mycotoxic porcine nephropathy; MAN -mycotoxic avian nephropathy; MNFA -mycotoxic nephropathy in farm animals; BEN -Balkan endemic nephropathy; OTA -ochratoxin A; OTα -ochratoxin α; PApenicillic acid; FB 1 -fumonisin B 1Int. J. Mol. Sci. 2008, 9

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Section: Methods Of Prophylaxis and Various Preventive Measures Inmentioning

confidence: 99%

Section: Methods Of Prophylaxis and Various Preventive Measures Inmentioning

confidence: 99%

Complex Etiology, Prophylaxis and Hygiene Control in Mycotoxic Nephropathies in Farm Animals and Humans

Stoev

2008

IJMS

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“…6 illustrates schematically the invasion of mycelium into kernels. Histochemical experiments supported conclusions of milling and pearling of wheat and barley kernels [2] as well as microbiological assays [4]. Ochratoxin A, a toxic metabolite of Aspergilli and Penicilliu in contaminated kernels, was found mainly in the same part of kernels and only small percentage in deeper layers and on surface [2].…”

Section: Resultsmentioning

confidence: 93%

Mycotoxins in cereal grain. Part X. Invasion of fungi mycelium into wheat and barley kernels

Chełkowski¹,

Cierniewska²

1983

Nahrung

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Histochemical examination of wheat kernels invaded by Aspergilli and Penicillia proved penetration of fungal mycelium into subaleurone and endosperm cells through aleurone layer cells. Walls of aleurone layer cells in invaded kernels were found to be thicker and split. Formation of spores in cleistothecia's in endosperm cells was found. The observation of kernels under a stereoscopic microscope was found to be a sensitive way to detect fungi invasion in cereal kernels.

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“…The knowledge of the opening of the lactone ring in alkaline media explains, at posteriori, the "strange" results obtained by Chelkowski et al [25,26]. These authors, treated by ammoniation at ambient temperature a rat feed contaminated by OTA.…”

Section: Otamentioning

confidence: 86%

Advantages and drawbacks of immunoaffinity columns in analysis of mycotoxins in food

Castegnaro

Tozlovanu

Wild

et al. 2006

Molecular Nutrition Food Res

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A number of countries are setting legislations on mycotoxins. In order to reduce dispute between importing and exporting countries, the analytical data should be as comparable as possible, especially when levels are close to the regulatory limits. The present trend in the analysis of mycotoxins is to use immunoaffinity column (IAC) as a clean-up and enrichment technique, and Association of Official Analytical Chemists and European Union have validated methods which address a few food commodities. This study describes our experience using both conventional and IAC approaches in the analysis of three mycotoxins. Aflatoxins (AFs): Aflatoxin G1 has been detected by liquid-liquid partitioning methods with HPLC detection as false-positive in some maize. On IACs, this compound behaves as an AF, lowering the amount of the AFs trapped. The problem was solved using either TLC or HPLC with detection in the Kobra cell. Depending on the additives to food during the processing and cooking, the AFs might appear as an opened ring not recognised by the antibody. Fumonisins (FB): Compounds interfering with the FB's antibodies were also observed while analysing breakfast cereals leading to underestimation of FB. Ochratoxin A (OTA): Depending on the food composition and extraction techniques, OTA is underestimated with IAC in some breakfast cereals and coffee. These data strengthen the necessity to validate methods using IAC for each complex matrix.

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Mycotoxins in cereal grain. Part IV. Inactivation of ochratoxin A and other mycotoxins during ammoniation

Cited by 40 publications

References 4 publications

Complex Etiology, Prophylaxis and Hygiene Control in Mycotoxic Nephropathies in Farm Animals and Humans

Complex Etiology, Prophylaxis and Hygiene Control in Mycotoxic Nephropathies in Farm Animals and Humans

Mycotoxins in cereal grain. Part X. Invasion of fungi mycelium into wheat and barley kernels

Advantages and drawbacks of immunoaffinity columns in analysis of mycotoxins in food

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