Myelinated Retinal Nerve Fibers in Children: OCT Imaging, Refractive Error and Vision

O'Brien, Scott; Sprunger, Derek T.; Lim, Maria E.; Wang, Jingyun

doi:10.4172/2155-9570.1000610

Cited by 1 publication

(2 citation statements)

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“… 22 , 23 Widespread MRNFs are usually associated with higher degrees of axial myopia. 24 , 25 Oh et al 26 found a strong association between localized scleral excavation and the distribution of MRNF, suggesting that the local visual deprivation caused by MRNF induces focal scleral excavation and contributes to the development of axial myopia. Schmidt et al 24 proposed that MRNF could blur retinal images and induce visual deprivation, leading to axial elongation.…”

Section: Discussionmentioning

confidence: 99%

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Macular Imaging Characteristics in Children with Myelinated Retinal Nerve Fiber and High Myopia Syndrome

Sarıgül Sezenöz,

Oto,

Akkoyun

et al. 2023

tjo

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Objectives: To investigate the macular imaging features in patients with unilateral myelinated retinal nerve fiber (MRNF) and high myopia syndrome. Materials and Methods: Six patients with unilateral MRNF and high myopia syndrome and 13 myopic controls were enrolled in this study. Spectral domain (SD) optical coherence tomography (OCT), SD enhanced depth imaging OCT, and OCT angiography (OCTA) imaging results of MRNF-affected eyes were compared with the fellow eyes and myopic controls. Results: All patients had abnormal foveal reflex and/or ectopia. No significant difference in retinal thickness parameters were noted between the groups. In OCT scans, posterior vitreous detachment (PVD) was observed in 4 out of the 6 MRNF-affected eyes. Regarding OCTA parameters, only a significant increase in acircularity index was noted in myelinated eyes (p=0.01). Conclusion: All patients demonstrated normal foveal contours, macular structure, and OCTA features except for a higher acircularity index. The incidence of PVD was notably increased in the myelinated eyes.

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Section: Discussionmentioning

confidence: 99%

“…The imaging characteristics of MRNF have been reviewed recently in the literature. O’Brien et al 25 demonstrated that peripapillary RNFL was significantly thicker in eyes with MRNF while macular thickness was within the normal range.…”

Section: Discussionmentioning

confidence: 99%