Myelodysplastic Syndromes: Pathophysiology

Gore, Steve; Warlick, Erica D.

doi:10.1002/9781444327359.ch6

Leukemias: Principles and Practice of Therapy 2010

DOI: 10.1002/9781444327359.ch6

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Myelodysplastic Syndromes: Pathophysiology

Steve Gore

Erica D. Warlick

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2013

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Cited by 1 publication

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Review of therapeutic options and the management of patients with myelodysplastic syndromes

Özcan

İlhan

Özcebe

et al. 2013

Expert Review of Hematology

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Myelodysplastic syndromes (MDS) are a poorly understood group of disorders caused by one or more genetic aberrations in the bone marrow-derived cell line responsible for hematopoiesis. Recent advances in genetic medicine have offered new insights into the epigenesis as well as the prognosis of MDS, but have not resulted in new or improved curative treatment options. Bone marrow transplantation, introduced before the advent of genetic medicine, is still the only potential cure. Advances in other medical and pharmaceutical areas have broadened the scope of supportive care and disease-modifying therapies, and treating physicians now have a broad range of disease management options depending on a patient's likely prognosis. There is now clear evidence that appropriate supportive care and therapeutic intervention can improve progression-free and overall survival of MDS patients.

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Review of therapeutic options and the management of patients with myelodysplastic syndromes

Özcan

İlhan

Özcebe

et al. 2013

Expert Review of Hematology

View full text Add to dashboard Cite

show abstract

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Myelodysplastic Syndromes: Pathophysiology

Cited by 1 publication

References 89 publications

Review of therapeutic options and the management of patients with myelodysplastic syndromes

Review of therapeutic options and the management of patients with myelodysplastic syndromes

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