2021
DOI: 10.1093/humrep/deaa328
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Myeloperoxidase inhibitor AZD5904 enhances human sperm function in vitro

Abstract: STUDY QUESTION Does AZD5904, a myeloperoxidase inhibitor (MPOi), have any effect on human sperm function in vitro? SUMMARY ANSWER AZD5904 improves sperm function in an in vitro model of oxidative stress (OS) and potentially offers a novel treatment approach for male infertility. WHAT IS KNOWN ALREADY Male infertility is an underlying or contributory cause in … Show more

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