Myocardial blood flow and oxygen consumption after aortic cross-clamping

Veen, Frederik H. van der; Vusse, Ger J.; Reneman, Robert S.

doi:10.1016/0022-4804(89)90142-x

Cited by 4 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have only included patients with a low risk profile in the study to prevent possible complications and to avoid unexpected additional effects on the measurements. As in our previous study [5], we again found a decreased resistance immediately after the onset of reperfusion due to metabolic changes within the ischemic myocardium, which can be defined as reactive hyperemia [19]. Increasing coronary artery resistances during reperfusion also could be demonstrated again in this study.…”

Section: Clinical Relevancesupporting

confidence: 88%

Coronary Vascular Stunning in Bypass Operations DuringReperfusion and Treatment with Nitroglycerin1

Kalweit

Schipke²,

Elsner³

et al. 2000

Thorac cardiovasc Surg

View full text Add to dashboard Cite

In routine heart surgery, coronary vascular constriction is regularly present during postischemic reperfusion despite myocardial protection measures. NTG abolishes this coronary vascular stunning only in part if systemically applicable dosages are given. High-dose intracoronary application of NTG relieves the coronary vasoconstriction completely, but the dosages needed cannot be applied systemically. In this study, vasoconstriction after reperfusion was markedly increased in patients with hypertension.

show abstract

Section: Clinical Relevancesupporting

confidence: 88%

Coronary Vascular Stunning in Bypass Operations DuringReperfusion and Treatment with Nitroglycerin1

Kalweit

Schipke²,

Elsner³

et al. 2000

Thorac cardiovasc Surg

View full text Add to dashboard Cite

show abstract

“…The arguments in favor of non-cardioplegic methods include greater simplicity and, in the case of intermittent aortic cross-clamping, the proven ability of the myocardium to withstand short periods of ischemia, interspersed with periods of physiological reperfusion, without necrosis or loss of function [ 10 , 11 ] . In our study we found that with single clamping, with average short time of each anastomosis, either distal 9.20±1.15 minutes or proximal 5.56 ± 1.44 minutes, and always interspersed with blood reperfusion of the aorta 3.56±0.62 minutes.…”

Section: Discussionmentioning

confidence: 99%

Improvement in cardioplegic perfusion technique in single aortic clamping - Initial Results

Sobral¹,

Júnior²,

Sá³

et al. 2014

Revista Brasileira De Cirurgia Cardiovascular

View full text Add to dashboard Cite

Introduction The most common method used for myocardial protection is administering cardioplegic solution in the coronary circulation. Nevertheless, protection may be achieved by intermittent perfusion of the coronary system with patient's own blood. The intermittent perfusion may be performed by multiple sequences of clamping and opening of the aortic clamp or due single clamping and accessory cannulation of the aortic root as in the improved technique proposed in this study, reperfusion without the need for multiple clamping of the aorta. Objective To evaluate the clinical outcome and the occurrence of neurological events in in-hospital patients submitted to myocardial revascularization surgery with the "improved technique" of intermittent perfusion of the aortic root with single clamping. Methods This is a prospective, cross-sectional, observational study that describes a myocardial management technique that consists of intermittent perfusion of the aortic root with single clamping in which 50 patients (mean age 58.5±7.19 years old) have been submitted to the myocardial revasculrization surgery under the proposed technique. Clinical and laboratory variables, pre- and post-surgery, have been assessed. Results The mean peak level of post-surgery CKMB was 51.64±27.10 U/L in the second post-surgery and of troponin I was 3.35±4.39 ng/ml in the fourth post-surgery, within normal limits. No deaths have occurred and one patient presented mild neurological disorder. Hemodynamic monitoring has not indicated any changes. Conclusion The myocardial revascularization surgery by perfusion with the improved technique with intermittent aortic root with single clamping proved to be safe, enabling satisfactory clinical results.

show abstract

Changes in myocardial high-energy phosphate stores and carbohydrate metabolism during intermittent aortic crossclamping in dogs on cardiopulmonary bypass at 34° and 25° C

Fh¹,

Gj²,

Willemsen³

et al. 1990

The Journal of Thoracic and Cardiovascular Surgery

View full text Add to dashboard Cite

Myocardial blood flow and oxygen consumption after aortic cross-clamping

Cited by 4 publications

References 20 publications

Coronary Vascular Stunning in Bypass Operations DuringReperfusion and Treatment with Nitroglycerin1

Coronary Vascular Stunning in Bypass Operations DuringReperfusion and Treatment with Nitroglycerin1

Improvement in cardioplegic perfusion technique in single aortic clamping - Initial Results

Changes in myocardial high-energy phosphate stores and carbohydrate metabolism during intermittent aortic crossclamping in dogs on cardiopulmonary bypass at 34° and 25° C

Contact Info

Product

Resources

About