Myocardial bridge characteristics and coronary atherosclerotic markers

Nafakhi, Hussein; Alam, Yasir; Al‐Mosawi, Abdulameer A.; Al-Nafakh, Hasan A.

doi:10.33678/cor.2019.005

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…Apart from the MB length and LAD coronary stenotic severity, no other risk factors were found to significantly affect abnormal FFRCT values in our study. Other studies have found that MB depth was also related to myocardial ischemia (Nafakhi et al, 2019) and that longer or deeper MB did not cause severe dynamic compression on the coronary artery and subsequently abnormal FFRCT values (Halliburton et al, 2011). Our study has analyzed patients with MB and patients with MB accompanied by atherosclerosis, whereas other authors only included LAD MB patients without any other abnormalities or without performing stratified analysis (Rubinshtein et al, 2013).…”

Section: Discussionmentioning

confidence: 97%

Quantitative computed tomography angiography evaluation of the coronary fractional flow reserve in patients with left anterior descending artery myocardial bridging

Zhang,

Tian,

et al. 2024

Clin Physio Funct Imaging

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PurposeTo quantitatively investigate the effect of myocardial bridge (MB) in the left anterior descending artery (LAD) on the fractional flow reserve (FFR).Materials and MethodsThree‐hundred patients with LAD MB who had undergone coronary artery CT angiography (CCTA) were retrospectively enroled, and 104 normal patients were enroled as the control. The CCTA‐derived fractional flow reserve (FFRCT) was measured at the LAD 10 mm proximal (FFR1) and 20–40 mm distal (FFR3) to the MB and at the MB location (FFR2).ResultsFFR2 and FFR3 of the MB (with BM only) and MBLA (with both MB and atherosclerosis) groups were significantly (p < 0.01) lower than those of the control. The FFR3 distal to the MB was significantly lower (p < 0.01) than that of the control. The FFRCT of the whole LAD in the MBLA group was significantly (p < 0.05) lower than that of the MB and control group (p < 0.05). MB length (OR 1.061) and MB muscle index (odds ratio or OR 1.007) were two risk factors for abnormal FFRCT, and MB length was a significant independent risk factor for abnormal FFRCT (OR = 1.077). LAD stenosis degree was a risk factor for abnormal FFRCT values (OR 3.301, 95% confidence interval [CI] 1.441–7.562, p = 0.005) and was also a significant independent risk factor (OR = 3.369, 95% CI: 1.392–8.152; p = 0.007) for abnormal FFRCT.ConclusionMB significantly affects the FFRCT of distal coronary artery. For patients with MB without atherosclerosis, the MB length is a risk factor significantly affecting FFRCT, and for patients with MB accompanied by atherosclerosis, LAD stenotic severity is an independent risk factor for FFRCT.

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Section: Discussionmentioning

confidence: 97%