2019
DOI: 10.1007/s10517-019-04623-9
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Myocardial Expression of SERCA2a and Structural and Functional Indices in Patients with Atrial Fibrillation

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Cited by 2 publications
(1 citation statement)
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“…Our current study suggests that novel therapeutic approaches may include inflammation-resolution strategies to prevent or cure the inflammatory status, which is commonly observed in AF and RHD. 2 , 38 , 52–55 In addition, SERCA2a is also dysregulated in both PAH and AF, 56 , 57 suggesting that strategies promoting the normal expression and activity of SERCA2a may contribute to preventing AF occurrence in RHD-induced arrhythmogenicity. In a rabbit model of left heart failure, upregulation of SERCA2a was associated with LA cardio-protection and reduction of atrial vulnerability to arrhythmogenicity.…”
Section: Discussionmentioning
confidence: 99%
“…Our current study suggests that novel therapeutic approaches may include inflammation-resolution strategies to prevent or cure the inflammatory status, which is commonly observed in AF and RHD. 2 , 38 , 52–55 In addition, SERCA2a is also dysregulated in both PAH and AF, 56 , 57 suggesting that strategies promoting the normal expression and activity of SERCA2a may contribute to preventing AF occurrence in RHD-induced arrhythmogenicity. In a rabbit model of left heart failure, upregulation of SERCA2a was associated with LA cardio-protection and reduction of atrial vulnerability to arrhythmogenicity.…”
Section: Discussionmentioning
confidence: 99%