Myocardial Infarction in an Infant With Transposition of the Great Vessels

Bernreiter, M

doi:10.1001/jama.1958.72990210007009c

Cited by 12 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…He believes that in the capillary circulation-area small patches of disseminated myocardial necroses can be found -as has been observed in the hearts studied here (48,4)). Similarly toxins and pharmaca are implicated in the genesis of perinuclear vacuoles (34,38,45,47,49).…”

Section: Discussionsupporting

confidence: 72%

See 1 more Smart Citation

The myocardium and its pathological state during the perinatal period and infancy

1983

Basic Res Cardiol

View full text Add to dashboard Cite

Summary311 hearts of fetuses, of premature and neonate babies, of preschool and school children were examined, irrespective of basic disease and cause of death. 63 hearts did not show any pathological alterations. They served as a control group. The fibers of 27 hearts of fetuses, premature and mature neonate babies were homogeneous" The close packing as well as the reduced number of myofibrils in some regions of the heart did not correspond to hearts of the same age and size of the control group.The following changes were found individually or in combination within the remaining 200 hearts:Perinuclear vacuoles and acidophilic fibers, acidophilic necroses, scars with or without calcification, interstitial haemorrhages, parietal thrombi, endocarditis and myocarditis.Prominent characteristics are perinuclear vacuoles, acidophilic fibers and acidophilic necroses. This combination often shows a characteristic morphological pattern: inner layer with acidophilic necroses, middle layer with acidophilia, and outer layer consisting of fibers with perinuclear vacuoles. This combination and the trilaminar arrangement lead to the conclusion that they may be caused by hypoxaemia, isehemia or hypoxidosis. Vacuoles and acidophilia are most likely to be reversible.According to their frequency, they appear to correlate with certain diseases (table 3), but none of the changes are specific for a certain disease:Perinuclear vacuoles, acidophilic fibers and acidophilic necroses very often exist with pulmonary diseases, with general infections and erythroblastosis. Interstitial haemorrhages and parietal thrombi can be traced in increasing numbers in traumas showing disseminated intravascular coagulation.Hypertrophic fibers are frequent in congenital heart disease, mostly in combination with acidophilic fibers and especially with scars.Further studies should aim at establishing a correlation between morphological and clinical observations. This paper suggests further studies in the field of morphology examining equivalent surgical material with the electron microscope.

show abstract

Section: Discussionsupporting

confidence: 72%

“…There exists also plenty of information on defects of the coronary circulation (1,5,14,23,25,30,35,41,44,53,56) and on myocardial changes related to congenital abnormalities of the heart and the great vessels (4,6,8,15,16,21,24,54).…”

Section: Introductionmentioning

confidence: 99%

The myocardium and its pathological state during the perinatal period and infancy

1983

Basic Res Cardiol

View full text Add to dashboard Cite

show abstract

“…Ischemic chest pain in the pediatric population is uncommon and can be secondary to both congenital defects (coronary arterial anomalies, aortic valvar and supravalvar stenosis, hypoplastic left heart syndrome, pulmonary atresia, or complete transposition of the great arteries) [5][6][7][8][9][10][11][12][13][14][15] or acquired diseases (eg, pericarditis, autoimmune vasculitis, Ka- wasaki disease, drug abuse and medications, trauma, endocarditis, or hyperlipidemia). [16][17][18][19][20][21][22][23][24] Angina with normal coronary anatomy in an otherwise healthy child or adolescent does not usually come to mind in the differential diagnosis of chest pain.…”

Section: Discussionmentioning

confidence: 99%

Myocardial Infarction in Healthy Adolescents

Lane

Ben-Shachar

2007

Pediatrics

View full text Add to dashboard Cite

Myocardial infarction can occur in adolescents with normal coronary arterial anatomy. Adolescents who present for emergency care with typical chest pain need electrocardiographic and cardiac enzyme workups. Those with results that are suggestive of acute infarction require additional workup. Coronary vasodilation therapy seems helpful, but given the lack of coronary thrombosis in these patients, thrombolytic therapy seems unwarranted. Long-term follow-up is necessary, and adjustments in therapy may be required with time.

show abstract

“…In each instance the symptomatology was completely relieved by operation. An unusual case of the anterior wall myocardial infarction pattern in the ECG occurred in a 7-week-old infant, with transposition of the great vessels (Bernreiter, 1958).…”

Section: Miscellaneousmentioning

confidence: 95%

Myocardial infarction and ischaemic heart disease in infants and children. Analysis of 29 cases and review of the literature.

Bor¹

1969

Archives of Disease in Childhood

View full text Add to dashboard Cite

Myocardial Infarction in an Infant With Transposition of the Great Vessels

Cited by 12 publications

References 0 publications

The myocardium and its pathological state during the perinatal period and infancy

The myocardium and its pathological state during the perinatal period and infancy

Myocardial Infarction in Healthy Adolescents

Myocardial infarction and ischaemic heart disease in infants and children. Analysis of 29 cases and review of the literature.

Contact Info

Product

Resources

About