Myocardial Infarction in Patients with and Without Covid-19: Comparison of Characteristics, Clinical Course and Outcome

Abstract

Background Covid-19 has quickly become a global health emergency. This infection can cause damage to various organs. Injury to myocardial cells is one of the most important manifestations of Covid-19. The clinical course and outcome of Acute Coronary Syndrome (ACS) are influenced by a variety of factors, including comorbidities and concomitant diseases. One of these acute concomitant diseases is Covid-19 which can affect the clinical course and outcome of acute Myocardial Infarction (MI). Methods In this cross-sectional study, the clinical course and outcome of MI and some of its effective factors in patients with and without Covid-19 were compared. 180 patients (129 males and 51 females) with the diagnosis of acute MI were included in the study. 80 patients of them had Covid-19 infection at the same time. Results Increase rate in creatinine, arrhythmia, and need for CPR (cardiopulmonary resuscitation) was significantly higher in the Covid-19 group (p value in all three cases < 0.001). Although decline in left ventricular EF (Ejection Fraction) was similar in both groups, the incidence of death was significantly higher in the Covid-19 group. Conclusions Based on this information, it appears that patients with ACS who are co-infected with Covid-19 infection need more essential care.