Myocardial Infarction incidence during national lockdown in two French provinces unevenly affected by COVID-19 outbreak: An observational study

Belle, Éric Van; Manigold, Thibault; Piérache, Adeline; Furber, Alain; Debry, Nicolas; Luycx-Bore, A.; Bauchart, Jean-Jacques; Nugue, Olivier; Huchet, François; Bic, Mathieu; Vinchon, F.; Sayah, Smaïn; Fournier, A; Decoulx, Eric; Mouhammad, Usman; Clerc, Jérôme; Manchuelle, Aurélie; Lazizi, Tahar; Chmaït, Akram; Jeannetteau, Julien; Hénon, Philippe; Bonin, Mickael; Dupret-Minet, Marie; Tirouvanziam, Ashok; Molcard, David; Arabucki, Fabien; Py, Antoine; Prunier, Fabrice; Delhaye, Cédric; Lemesle, Gilles; Schurtz, Guillaume; Cosenza, Alessandro; Spillemaeker, Hugues; Verdier, Basile; Denimal, Tom; Pamart, Thibault; Sylla, Habib; Janah, Dany; Aouate, David; Porouchani, Sina; Guillez, Valérie; Bonnet, Guillaume; Ternacle, Julien; Labreuche, Julien; Cayla, Guillaume; Vincent, Flavien

doi:10.1016/j.lanepe.2021.100030

Cited by 19 publications

(17 citation statements)

References 13 publications

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“…This could be a sign of postponed ED presentation or collateral damage. These findings are in line with other studies reporting decreased numbers of hospital admissions and ED presentations with acute coronary syndrome and MI during the first pandemic wave [ 10 – 12 , 16 , 26 – 29 ]. There was no clear trend for a compensatory increase after the initial lockdown in 2020.…”

Section: Discussionsupporting

confidence: 92%

Medical and cardio-vascular emergency department visits during the COVID-19 pandemic in 2020: is there a collateral damage? A retrospective routine data analysis

et al. 2022

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Background In this retrospective routine data analysis, we investigate the number of emergency department (ED) consultations during the COVID-19 pandemic of 2020 in Germany compared to the previous year with a special focus on numbers of myocardial infarction and acute heart failure. Methods Aggregated case numbers for the two consecutive years 2019 and 2020 were obtained from 24 university hospitals and 9 non-university hospitals in Germany and assessed by age, gender, triage scores, disposition, care level and by ICD-10 codes including the tracer diagnoses myocardial infarction (I21) and heart failure (I50). Results A total of 2,216,627 ED consultations were analyzed, of which 1,178,470 occurred in 2019 and 1,038,157 in 2020. The median deviation in case numbers between 2019 and 2020 was − 14% [CI (− 11)–(− 16)]. After a marked drop in all cases in the first COVID-19 wave in spring 2020, case numbers normalized during the summer. Thereafter starting in calendar week 39 case numbers constantly declined until the end of the year 2020. The decline in case numbers predominantly concerned younger [− 16%; CI (− 13)–(− 19)], less urgent [− 18%; CI (− 12)–(− 22)] and non-admitted cases [− 17%; CI (− 13)–(− 20)] in particular during the second wave. During the entire observation period admissions for chest pain [− 13%; CI (− 21)–2], myocardial infarction [− 2%; CI (− 9)–11] and heart failure [− 2%; CI (− 10)–6] were less affected and remained comparable to the previous year. Conclusions ED visits were noticeably reduced during both SARS-CoV-2 pandemic waves in Germany but cardiovascular diagnoses were less affected and no refractory increase was noted. However, long-term effects cannot be ruled out and need to be analysed in future studies. Graphical abstract

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Section: Discussionsupporting

confidence: 92%

Medical and cardio-vascular emergency department visits during the COVID-19 pandemic in 2020: is there a collateral damage? A retrospective routine data analysis

et al. 2022

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“…Consistent with previous reports, we observed a decrease in hospitalisations for AMI and heart failure (figure 3B). Studies worldwide have reported a significant decrease in admissions for cardiovascular diseases during the pandemic 11 32 33. While studies from the USA and Europe reported increased rates of in-hospital mortality,33 34 a study from Japan did not report a notable increase 19.…”

Section: Discussionmentioning

confidence: 93%

Impact of COVID-19 pandemic on healthcare service use for non-COVID-19 patients in Japan: retrospective cohort study

Yamaguchi

Okada

Sunaga³

et al. 2022

BMJ Open

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ObjectivesWe aimed to investigate the impact of the first and second waves of the COVID-19 pandemic on healthcare service use by non-COVID-19 patients.DesignRetrospective cohort study.SettingHospital-based claims database from anonymised hospitals in Japan.ParticipantsPatients (n=785 495) who visited and/or were hospitalised in 26 anonymised hospitals in Japan between January 2017 and November 2020.Outcome measuresWe compared changes in the monthly number of hospitalisations (overall or by diagnosis), outpatient visits, endoscopic fibrescopies (EFs), rehabilitations, outpatient chemotherapy treatments, maintenance haemodialysis treatments and outpatient prescriptions between pre-COVID-19 years and the same period in 2020.ResultsThe overall number of hospitalisations and outpatient visits decreased by 27% and 22%, respectively, in May 2020, of which the most substantial decrease was observed in the paediatrics department (65% and 51%, respectively). The number of hospitalisations for respiratory diseases, circulatory diseases, malignant neoplasms and digestive diseases decreased by a maximum of 55%, 32%, 10% and 26%, respectively, in 2020. The number of hospitalisations for non-COVID-19 pneumonia in patients aged <16 years, patients aged ≥16 years and patients with asthma decreased by 93%, 43% and 80%, respectively, in May 2020. EFs and outpatient rehabilitations decreased by >30%. In contrast, outpatient chemotherapy and maintenance haemodialysis treatments decreased by <10%, if at all. Outpatient prescriptions decreased by a maximum of 20% in 2020, with the largest decrease observed in drugs for obstructive airway diseases and cough and cold preparations.ConclusionsThe use of healthcare services by non-COVID-19 patients was most affected during the first wave of the COVID-19 pandemic in May 2020. The number of hospitalisations for respiratory diseases, particularly non-COVID-19 pneumonia and asthma, drastically decreased, while the number of hospitalisations and outpatient chemotherapies for malignant neoplasms or maintenance haemodialysis was less affected.

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“…These elements could be exacerbated during the pandemic, leaving women in a riskier situation. A possible solution to this issue could be rigorous public health campaigns through local media, which proved to be an effective way to promote awareness on the timely care of acute cardiovascular events during the pandemic in the USA and France 23 24…”

Section: Discussionmentioning

confidence: 99%

Changes in cardiovascular mortality in Chile during the COVID-19 pandemic

Chang

Zitko

Passi-Solar

et al. 2022

Heart

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ObjectivesThe COVID-19 pandemic has impacted regular cardiovascular healthcare access and delivery. Service utilisation has declined, and excess cardiovascular mortality has been reported in several countries. We aim to estimate excess cardiovascular deaths in Chile during 2020.MethodsWe collected mortality data from the Chilean Department of Statistics and Health Information and refined them using the maps of Global Burden of Disease Studies in 2017 and 2010. We conducted a time series analysis using quasi-Poisson distribution to predict cardiovascular mortality in 2020 and compared it with observed numbers and calculated attributable fractions (AFs) with 95% uncertainty intervals, as a whole and by sex, age group and type of cardiovascular disease.ResultsDuring 2015–2020, 173 283 cardiovascular deaths were recorded, with 28 141 deaths in 2020. The observation in 2020 was lower than our projection in the overall data (−4.0% (−5.0% to −2.8%)) and in male (−11.7% (−13% to −10.3%)). However, positive AFs were noted among female (5.0% (3.2% to 6.8%)), people in age group 80–89 years (11.0% (8.6% to 13.5%)) and people who died from hypertensive heart diseases (18.9% (14.7% to 23.5%)).ConclusionsLess overall cardiovascular deaths were observed in 2020 compared with our projection, possibly associated with competing risks from COVID-19 infection in men. Nonetheless, excess cardiovascular deaths were observed among women, people in the age group 80–89 years and people who died from hypertensive heart diseases suggesting possible negative cardiovascular impacts brought by the pandemic on these vulnerable groups.

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Myocardial Infarction incidence during national lockdown in two French provinces unevenly affected by COVID-19 outbreak: An observational study

Cited by 19 publications

References 13 publications

Medical and cardio-vascular emergency department visits during the COVID-19 pandemic in 2020: is there a collateral damage? A retrospective routine data analysis

Medical and cardio-vascular emergency department visits during the COVID-19 pandemic in 2020: is there a collateral damage? A retrospective routine data analysis

Impact of COVID-19 pandemic on healthcare service use for non-COVID-19 patients in Japan: retrospective cohort study

Changes in cardiovascular mortality in Chile during the COVID-19 pandemic

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