Myocardial infarction with normal coronary arteries is common and associated with normal findings on cardiovascular magnetic resonance imaging: results from the <scp>S</scp>tockholm <scp>M</scp>yocardial <scp>I</scp>nfarction with <scp>N</scp>ormal <scp>C</scp>oronaries study

Collste, Olov; Sörensson, Peder; Frick, Mats; Agewall, Stefan; Daniel, Maria; Henareh, Logman; Ekenbäck, Christina; Eurenius, Lars; Guiron, C.; Jernberg, Tomas; Hofman-Bang, Claes; Malmqvist, Karin; Nagy, Edit; Arheden, Håkan; Tornvall, Per

doi:10.1111/j.1365-2796.2012.02567.x

Cited by 133 publications

(122 citation statements)

References 22 publications

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“…These data are similar to our study results, but they also considered diabetic patients, which could create a possible bias [15].…”

Section: Discussionsupporting

confidence: 91%

“…Therefore, it seems that in these patients a rise in troponin values did not determine a morphological alteration evaluated with CE CMR, probably because the myocardial damage is so modest that it remains unrecognized. This could explain the low levels of mortality attributed to MINCA in the literature: for Bugiardini et al [16], for example, MINCA would show an incidence of myocardial infarction and death at 12 months ranging from 2.2 to 3.3 % [15]. In these patients, it is reasonable to assume a favorable prognostic course with a good outcome in the medium and long term [3,8].…”

Section: Discussionmentioning

confidence: 95%

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Diagnostic value of contrast-enhanced cardiac magnetic resonance in patients with acute coronary syndrome with normal coronary arteries

2015

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“…These data are similar to our study results, but they also considered diabetic patients, which could create a possible bias [15].…”

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 95%

Diagnostic value of contrast-enhanced cardiac magnetic resonance in patients with acute coronary syndrome with normal coronary arteries

2015

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“…For patients without evidence of coronary artery disease or a pseudoinfarctual presentation, CMR is a useful noninvasive diagnostic tool for the clinical diagnosis of myopericardial inflammatory syndromes and to rule out acute myocardial infarction with normal coronary arteries. 16,[24][25][26][27][28] In these cases, the diagnostic utility of EMB is clearly reduced for clinicians. Although EMB may establish a definite diagnosis, it is difficult to justify its clinical utility in patients with myopericarditis/perimyocarditis 48 Circulation…”

Section: Discussionmentioning

confidence: 99%

Good Prognosis for Pericarditis With and Without Myocardial Involvement

et al. 2013

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Background— The natural history of myopericarditis/perimyocarditis is poorly known, and recently published studies have presented contrasting data on their outcomes. The aim of the present article is to assess the prognosis of myopericarditis/perimyocarditis in a multicenter, prospective cohort study. Methods and Results— A total of 486 patients (median age, 39 years; range, 18–83 years; 300 men) with acute pericarditis or a myopericardial inflammatory syndrome (myopericarditis/perimyocarditis; 85% idiopathic, 11% connective tissue disease or inflammatory bowel disease, 5% infective) were prospectively evaluated from January 2007 to December 2011. The diagnosis of acute pericarditis was based on the presence of 2 of 4 clinical criteria (chest pain, pericardial rubs, widespread ST-segment elevation or PR depression, and new or worsening pericardial effusion). Myopericardial inflammatory involvement was suspected with atypical ECG changes for pericarditis, arrhythmias, and cardiac troponin elevation or new or worsening ventricular dysfunction on echocardiography and confirmed by cardiac magnetic resonance. After a median follow-up of 36 months, normalization of left ventricular function was achieved in >90% of patients with myopericarditis/perimyocarditis. No deaths were recorded, as well as evolution to heart failure or symptomatic left ventricular dysfunction. Recurrences (mainly as recurrent pericarditis) were the most common complication during follow-up and were recorded more frequently in patients with acute pericarditis (32%) than in those with myopericarditis (11%) or perimyocarditis (12%; P <0.001). Troponin elevation was not associated with an increase in complications. Conclusions— The outcome of myopericardial inflammatory syndromes is good. Unlike acute coronary syndromes, troponin elevation is not a negative prognostic marker in this setting.

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“…Main differential diagnoses in this setting include myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies, although other less common conditions such as pheochromocytoma should be also considered. [3][4][5][6] Takotsubo cardiomyopathy may masquerade as an acute coronary syndrome. 1 7 It is diagnosed in about 2.5% of patients with suspected acute coronary syndrome and was recently shown to be responsible for several thousands of hospital admissions each year in the United States.…”

Section: Answers 1 What Is the Diagnosis? Short Answermentioning

confidence: 99%