Myocardial performance index derived from pre-ejection period as a novel and useful predictor of cardiovascular events in atrial fibrillation

Chu, Chun-Yuan; Lee, Wen-Hsien; Hsu, Po-Chao; Lee, Hung-Hao; Chiu, Chih-Yi; Su, Ho‐Ming; Lin, Tsung-Hsien; Lee, Chee-Siong; Yen, Hsueh‐Wei; Voon, Wen‐Chol; Lai, Wen‐Ter; Sheu, Sheng‐Hsiung

doi:10.1016/j.jjcc.2014.07.014

Cited by 9 publications

(7 citation statements)

References 33 publications

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“…Previous studies have utilized the PEP-derived MPI to evaluate LV function in AF patients. 8 , 9 , 29 Recently, it was reported that the PEPa-derived MPI was a useful predictor of adverse cardiovascular events, and could offer an additional prognostic benefit over conventional clinical and echocardiographic parameters in patients with AF. 9 …”

Section: Discussionmentioning

confidence: 99%

“… 8 PEP interval was measured from the onset of QRS to the onset of the systolic mitral annular velocity pattern. Su et al 9 defined the “PEPa-derived MPI” in patients with AF; it is calculated as the ratio of PEPa along with IVRTa to ETa. In a recent study, it was reported that the PEPa-derived MPI was a useful predictor of adverse cardiovascular events, and could offer an additional prognostic benefit over conventional clinical and echocardiographic parameters in patients with AF.…”

Section: Introductionmentioning

confidence: 99%

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Relationship Between Tei Index and PEP-Derived Myocardial Performance Index in Sinus Rhythm

et al. 2015

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The goal of this study was to evaluate the preejection time (PEP)-derived myocardial performance index (MPI) in hypertensive (HT) patients with sinus rhythm and its relationship to the classic Tei index.One hundred five patients were enrolled in the study (65 HT and 40 control subjects). The mean age of all patients was 50.5 ± 15 years and 60% were female. Echocardiography was performed on all patients. MPI was measured with the classic Tei method (MPI-Tei index) and the PEP-derived MPI method by using tissue Doppler echocardiography. Although the MPI-Tei index is defined as the ratio of isovolumetric contraction time (IVCT) along with isovolumetric relaxation time (IVRT) to ejection time (ET), PEP-derived MPI is defined as the ratio of PEP and IVRT to ET. We compared echocardiographic data between the HT group and the control group.MPI-Tei index and the PEP-derived MPI values were higher in the HT group compared with controls (0.52 ± 0.10 vs 0.39 ± 0.07, P < 0.001, and 0.51 ± 0.09 vs 0.39 ± 0.07). PEP-derived MPI was strongly correlated with the MPI-Tei index (r = 0.945, P < 0.001).Our study determined that the PEP-derived MPI might be used in the evaluation of left ventricular function in patients with HT, similar to the classic MPI-Tei index.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Relationship Between Tei Index and PEP-Derived Myocardial Performance Index in Sinus Rhythm

et al. 2015

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“…In another study that observed 190 patients with AF, increased average E/e' was related to death and hospitalization for heart failure in univariate analysis (p<0.001) [55] . In another observational study that prospectively followed 196 consecutive patients with AF for about 17 months, an abnormal value for average E/e' was associated with sudden death, stroke and hospitalization for heart failure (p =0.001), after adjusting for chronic heart failure (p = 0.002) and the myocardial performance index (p = 0.004) [56] . Similar results have been reported in another observational study that followed 252 consecutive patients with AF for 21 months [57] .…”

Section: Relevance Of E/e' In Risk Stratification In Patients With Afmentioning

confidence: 98%

Clinical Relevance of the Spectral Tissue Doppler E/e’ Ratio in the Management of Patients with Atrial Fibrillation: a Comprehensive Review of the Literature.

Arquès¹

2018

Journal of Atrial Fibrillation

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Atrial fibrillation is the most common cardiac rhythm disorder observed in clinical practice. It carries high morbidity and mortality rates, primarily related to heart failure, stroke and death. Validation of noninvasive markers in the diagnosis of heart failure with preserved ejection fraction and risk stratification is relevant in this clinical setting. The spectral tissue Dopplerderived E/e' ratio is a simple and reproducible index, which has been validated in noninvasive assessment of left ventricular diastolic pressures, regardless of rhythm. Septal E/e' >11 is a good predictor of invasively determined left ventricular diastolic pressure >15 mmHg in patients with atrial fibrillation. Several studies have validated the clinical relevance of abnormal values for E/e' at rest and during exercise in the diagnosis and risk stratification of heart failure with preserved ejection fraction in patients with atrial fibrillation. Increased E/e' value is associated with adverse outcome (death, left atrial appendage thrombus, stroke and heart failure) in patients with atrial fibrillation and predicts arrhythmia recurrence after cardioversion and catheter ablation. In conclusion, E/e' by spectral tissue Doppler is clinically relevant in the clinical management of any patients with atrial fibrillation referred for transthoracic Doppler echocardiography.

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“…15 Eight studies compared echocardiographic indices of systolic function with clinical parameters or surrogate biomarkers. [16][17][18][19][20][21][22][23] In 1293 AF patients who had suffered a myocardial infarction, lower LVEF (estimated using an echocardiographic wall motion score) was associated with an increase in the risk of 30-day mortality (8% for patients with LVEF >50%, 10% for LVEF 36-50%, 24% for LVEF 26-35% and 40% for LVEF <25%). 19 However, lower LVEF did not appear to predict long-term mortality in AF patients.…”

Section: Echocardiographymentioning

confidence: 99%

Cardiac Imaging to Assess Left Ventricular Systolic Function in Atrial Fibrillation

Bunting

O’Connor

Steeds

et al. 2021

The American Journal of Cardiology

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Myocardial performance index derived from pre-ejection period as a novel and useful predictor of cardiovascular events in atrial fibrillation

Abstract: In AF patients, the PEPa-derived MPI was a useful predictor of adverse cardiovascular events and could offer an additional prognostic benefit over conventional clinical and echocardiographic parameters.

Cited by 9 publications

References 33 publications

Relationship Between Tei Index and PEP-Derived Myocardial Performance Index in Sinus Rhythm

Relationship Between Tei Index and PEP-Derived Myocardial Performance Index in Sinus Rhythm

Clinical Relevance of the Spectral Tissue Doppler E/e’ Ratio in the Management of Patients with Atrial Fibrillation: a Comprehensive Review of the Literature.

Cardiac Imaging to Assess Left Ventricular Systolic Function in Atrial Fibrillation

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