Myofibroblastoma of the Male Breast: a Typical Case Report and Narrative Review

Abstract

Myofibroblastoma (MFB) is a rare stromal benign tumor that arises from the breast tissue, composed by fibroblasts, myofibroblasts and adipocytes. MFB typically presents as a solitary, painless mass in the breast, predominates in 60-80 yearsold adult males and is rarer in postmenopausal women. It could be diagnosed by a combination of imaging and pathological tests, even if its imaging features are nonspecific, often leading to misdiagnosis. Biopsy is always needed for definitive diagnosis. Wide local excision, with no need of sentinel lymph node biopsy, is curative since local recurrence is extremely low and has been reported to be less than 1.5%. We report herein the case of MFB in a 61-year old male presenting with a nodule on the left breast and review the literature focusing on differential diagnosis.