Myofibroma: From protein losing enteropathy to liver tumor

Tewari, Deepali; Tewari, V.K.; Berezin, Stuart; Halata, Michael S.

doi:10.1016/j.epsc.2014.07.003

Cited by 1 publication

(3 citation statements)

References 42 publications

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“…2,4,5 Clinically, myofibroma lesions are classified into solitary and multicentric forms, designated as myofibroma and myofibromatosis respectively. 1,3,4,6 Myofibroma is usually benign in nature and mostly affects the skin and subcutaneous tissue, while myofibromatosis is predominantly more severe as it usually involves the internal organs. 1,3,4,7,8 Therefore, the disease can also be classified according to the origin of the lesion as dermatological or visceral.…”

Section: Introductionmentioning

confidence: 99%

“…Subsequently, several different terms were described including "congenital multiple fibromatosis," "diffuse congenital fibromatosis," "congenital generalized fibromatosis," and "infantile myofibromatosis." 1,6 The current consensus is to use the term "myofibroma. "…”

Section: Introductionmentioning

confidence: 99%

“…Historically, myofibroma lesions were labeled as “congenital fibrosarcoma” by Williams and Schrum in 1951. Subsequently, several different terms were described including “congenital multiple fibromatosis,” “diffuse congenital fibromatosis,” “congenital generalized fibromatosis,” and “infantile myofibromatosis.” 1,6 The current consensus is to use the term “myofibroma.”…”

Section: Introductionmentioning

confidence: 99%

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Infantile Myofibroma of the Frontal Bone: A Case Report

Alawi,

Abri,

Shaqsi

et al. 2024

FACE

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Background: Infantile myofibroma stands as the most prevalent fibrous neoplasm within the pediatric population, despite its rarity. The majority of these tumors manifest within the initial 2 years of life. Clinically, myofibroma lesions are classified into solitary and multicentric tumors. Methods: We present a case of infantile myofibroma located within the frontal bone of a 16-month-old infant. Initial evaluation of the swelling and its spread was conducted using CT and MRI scans. Subsequently, the diagnosis was confirmed through a core needle biopsy. Results: The tumor underwent surgical excision with 1 cm safety margin and immediate reconstruction with strips of calvaria bone graft. Histopathology of the specimen showed complete tumor clearance with actual margin of 7 mm. Conclusion: The surgical resection of cranial benign bone tumors should be meticulously planned with a multidisciplinary approach. Wherever possible, immediate reconstruction should be conducted to avoid the morbidity of a subsequent procedure.

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