Myopericytoma arising adjacent to the common carotid artery: Case report and systematic review of deep located neck myopericytomas

Calleros, Héctor Manuel Prado; Galarza-Lozano, David; Arrieta-Gómez, José R; Pombo-Nava, Alejandro; Parraguirre-Martínez, Sara; Gutiérrez, Carlos Jimenez

doi:10.1002/hed.24455

Cited by 8 publications

(5 citation statements)

References 28 publications

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“…Myopericytomas are not accompanied by pain; however, most intravascular myopericytomas are characterized by slow growth (8 months-30 years) and pain, which are reported in about half of the cases. [4,[16][17][18][19][20][21][22] Tumors that occur on the face and feet have rarely been reported to be painful. [23][24][25][26][27] McMenamin and Calonje [4] assumed that pain is caused by a tumor thrombus, as in our case.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous deep vein thrombosis of the upper arm due to an intravascular myopericytoma: A case report and literature review

Jang,

Yoo

2023

Medicine

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Introduction: Intravascular myopericytomas are a rare type of myopericytomas. In most previously reported cases, these were benign, occurred on the legs or neck, and had low recurrence rates. We have described a unique case of an intravascular myopericytoma that caused spontaneous deep vein thrombosis. Main symptoms, important clinical findings, and main diagnoses: A 37-year-old man presented with sudden-onset pain and swelling in the upper arm; physical examination revealed a 10 cm, palpable, firm, and mobile lesion in the upper arm. A biopsy revealed intravascular myopericytoma; immunohistological examination revealed a lesion in the lumen of the basilic vein. The tumor comprised abundant myxoid stroma with spindle cells proliferating in a concentric perivascular manner around the blood vessel. The tumor cells stained positive for CD34 and smooth muscle actin. Therapeutic interventions and outcomes: The patient underwent total excision of the mass under local anesthesia; no recurrence was observed thereafter. A literature review was performed using PubMed and Google Scholar; the key terms were “intravascular myopericytoma” and “IVMP.” Nineteen cases of intravascular myopericytomas across 14 articles published between January 2002 and January 2022 were identified. These involved 11 men and 7 women (sex was unknown in 1 case); the ages were 22 to 80 years (mean: 59.8 ± 14 years). In most cases, the tumor was slow-growing, and the etiology was previous surgical history or trauma. No pain was reported by patients with tumors on the face or feet, and no recurrence was observed after surgery in any of the reported cases. Immunohistochemical staining for smooth muscle actin, h-caldesmon, calponin, and CD34 was performed for differential diagnosis. Contrary to the slow-growing nature reported in the literature, the nature related to growing in the present case was unclear that lesion was discovered because of sudden pain caused by thrombosis. However, the diagnostic method and recurrence rate in our case were similar to those in the previously reported cases. Conclusion: Our case shows that although intravascular myopericytomas are rare, they can cause spontaneous thrombosis. They have low recurrence rates after complete resection. Spontaneous deep vein thrombosis that occurs in rare locations must be treated after determining the causes.

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Section: Discussionmentioning

confidence: 99%

Spontaneous deep vein thrombosis of the upper arm due to an intravascular myopericytoma: A case report and literature review

Jang,

Yoo

2023

Medicine

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“…Surgical resection is the most effective treatment for MPC. Most patients with MPC have better postoperative recovery and less local recurrence ( 23 ). After surgical resection of this tumor, a few recurrences have been reported in the literature, which could be related to inadequate removal of the tumor due to difficulty in complete detachment from neighboring tissues or the formation of new primary lesions ( 11 ).…”

Section: Discussionmentioning

confidence: 99%

Pontine Myopericytoma: Case Report and Literature Review

et al. 2022

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Myopericytoma (MPC) is a benign soft tissue tumor that develops from perivascular myoid cells and is part of the perivascular tumor group. MPC most commonly occurs in the subcutaneous soft tissues of the extremities, while intracranial MPC is remarkably rare. Herein, we report the case of a 45-year-old woman with myopericytoma who had a 2-week history of recurrent dizziness. Magnetic resonance imaging (MRI) revealed an irregular mass in the pons, with nodular enhancement of the mass on contrast-enhanced scans. The mass was considered a vascular lesion and was highly suspected to be a hemangioblastoma, prompting surgical intervention for the patient. The postoperative pathological report corrected the initial diagnosis, hemangioblastoma, to MPC. Intracranial MPC is extremely rare and there are no detailed imaging sources for this condition; furthermore, MPC occurrence in the pons has not been reported previously. This report presents the etiological characteristics intracranial MPC as visualized through MRI data alongside a comparative discussion on other reported diagnoses that resemble MPC. The case findings will provide a more widespread understanding for radiologists regarding the differential diagnosis of intracranial blood-rich supply lesions.

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“…We report what we believe is the first documented case of myopericytoma in the mastoid with recurrence of the tumor. Myopericytoma of the soft tissue and skin have been reported as arising in the extremities, and very rarely in the head and neck (3). Reports in the temporal bone are very limited: one case has been reported in the internal auditory canal, one in the external ear, and two in the temporal bone (site unspecified) (4–6).…”

Section: Discussionmentioning

confidence: 99%