Myositis Associated With Influenza B Infections

Dietzman, Dale E.; Schaller, Jane G.; Ray, C. George; Reed, Marie E

doi:10.1203/00006450-197404000-00501

Cited by 38 publications

(51 citation statements)

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“…Benign acute childhood myositis tends to be more prevalent in the late winter and early spring, [1][2][3] supporting the theory that its underlying cause is viral illness. 2,4,5 As in our patient, most cases in countries of northern latitudes occur in March and April.…”

Section: Discussionmentioning

confidence: 53%

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A stiff-legged gait: benign acute childhood myositis

Jain¹,

Kolber²

2009

Canadian Medical Association Journal

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Section: Discussionmentioning

confidence: 53%

“…2,4,5 As in our patient, most cases in countries of northern latitudes occur in March and April. [1][2][3] Generally, this condition affects school- …”

Section: Discussionmentioning

confidence: 99%

A stiff-legged gait: benign acute childhood myositis

Jain¹,

Kolber²

2009

Canadian Medical Association Journal

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“…Early occurrence of IAM in the course of influenza and the absence of inflammatory infiltrates argue against an important role of an immune-mediated process. Risk factors for IAM brought forward in the literature include muscle tropism of specific influenza virus strains [35], male gender [35], and primary infection [10,18,24,35] with an influenza virus.…”

Section: Discussionmentioning

confidence: 99%

“…The median age was 9.3 years (range [3][4][5][6][7][8][9][10][11][12][13][14]. In contrast to uncomplicated cases of IAM, which had a male predominance of 2:1 and usually affected the lower extremities, influenza-associated rhabdomyolysis occurred more often in girls (4:1), and pain and tenderness were mostly diffuse.…”

Section: Review Of the Literaturementioning

confidence: 99%

Influenza-Associated Myositis in Children

et al. 2004

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Background: Influenza-associated myositis (IAM) is an infrequent and poorly known complication of influenza virus infection in children. The aim of this study was to describe five cases of IAM and to review the literature on IAM in children. Patients and Methods:We conducted a retrospective analysis of cases of IAM diagnosed at two university children's hospitals in Switzerland during two consecutive influenza seasons. Findings were compared with 39 individual case reports and five publications summarizing an additional 272 cases identified by a medical online library (MEDLINE) search. Results: Overall, 316 cases were analyzed. IAM typically occurred in school-aged children with a 2:1 male predominance. Influenza B and A viruses were identified in 76% and 24% of cases, respectively. The median interval between onset of influenza and onset of IAM was 3 days (range 0-18). The calf muscles were involved alone or together with other muscle groups in 69% and 31% of cases, respectively. Blood creatine phosphokinase (CPK) concentration was invariably elevated. Median duration to clinical recovery was 3 days (range 1-30). Rhabdomyolysis occurred in ten of 316 patients (3%), was more common in girls (80%), more often associated with influenza A (86%), and led to renal failure in eight patients (80%). Conclusion: Clinical and laboratory findings of IAM are highly characteristic and allow a rapid diagnosis during the influenza season.

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“…Parvovirus, the virus causing Fifth disease, can be accompanied by arthritis in one or a number of joints (121). Influenza B infection can be followed by an acute transient "myositis" of the calf muscles (122). Childhood leukemia, and indeed any of the childhood malignances, can be the basis for frank arthritis, sometimes with other systemic complaints also reminiscent of rheumatic disease (123).…”

Section: Pediatric Rheumatology 1970 -2004mentioning

confidence: 99%