Myxoedema induced by Thiouracil

Abstract

MEDICAL MEMORANDA MBDICAL JOURNAL July 5.-The patient regained consciousness and became quieter.The neck rigidity persisted, but the temperature had dropped to 99.4°F. July 6.-Temperature normal; patient able to talk rationally and take nourishment. The strabismus and inequality of pupils disappeared and the facial paresis cleared up.July 8.-The patient received the last injection of penicillin at 4 p.m., and by 8 p.m. he developed a marked oedema of the anterior aspect of the neck, extending from the root of the neck to the thyroid cartilage. The temperature had risen to 99.2' F. The neck rigidity was still present; but was much less marked. Sulphadiazine 1 g. was given 4-hourly, and by the next morning the oedema had subsided.