Myxoma of the Breast in a Male Patient

Angiomyxoma of the Breast

“…4,12,13 Mutations or large deletions in PRKAR1A, or loss of PRKAR1A by immunohistochemistry, are found in both syndromic and sporadic forms of these tumor types. 4,10,11,13,14 Despite Carney and Toorkey's original description, these lesions, when occurring in breast, have not been well-characterized in subsequent literature, and there are just a few case reports of similar myxoid lesions arising in the nipple and breast, [15][16][17][18][19] described under various diagnostic terms such as myxoma of breast, nodular mucinosis, nodular/lobular myxoid change, and myxoid fibroadenoma . In our clinical practice, we have encountered cases of "superficial" angiomyxoma arising in various locations within the breast region, including in the dermis and/or subcutis, or deeper within breast parenchyma.…”