Myxoma of the Left Atrium

Aldridge, Harold E.; Greenwood, W. F.

doi:10.1136/hrt.22.2.189

Cited by 79 publications

(39 citation statements)

References 22 publications

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“…A normal heart rhythm, however, is commonly associated with atrial myxomas (Aldridge and Greenwood, 1960), and suspicion should be aroused whenever cerebral embolism occurs in a patient with a non-fibrillating heart. A more significant but less commonly recorded finding is a cardiac arrhythmia which is related to changes in body position.…”

Section: Summary Of Cases Reported Previouslymentioning

confidence: 99%

“…Although rare-only 350 cases had been reported by 1965 (Newman, Cordell, and Prichard, 1966)-it is a histologically benign growth that is completely curable if promptly recognized and surgically removed. From various reviews of the clinical manifestations of this neoplasm (Aldridge and Greenwood, 1960;Goodwin, 1963;Silverman, Olwin, and Graettinger, 1962), systemic embolization is known to occur in 40 to 45 % of patients. Emboli are frequently multiple and lodge in many sites, but in approximately one-half of the cases the brain is the target organ (Silverman et al, 1962).…”

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confidence: 99%

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Atrial myxoma: a treatable cause of stroke.

Maroon¹,

Campbell²

1969

Journal of Neurology, Neurosurgery & Psychiatry

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Section: Summary Of Cases Reported Previouslymentioning

confidence: 99%

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confidence: 99%

Atrial myxoma: a treatable cause of stroke.

Maroon¹,

Campbell²

1969

Journal of Neurology, Neurosurgery & Psychiatry

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“…The heart rate was normal, and none of the clinical findings of pulmonary hypertension were present. The presence of sinus rhythm excluded an important myocardial factor (Fleming and Wood, 1959). A large right ventricle, which is always associated with congestive failure or tricuspid regurgitation, may displace the mitral valve posteriorly: no evidence of either of these conditions was present.…”

Section: Discussionmentioning

confidence: 98%

“…The clinical diagnosis in the first three cases (Aldridge and Greenwood, 1960) was mitral stenosis. In the fourth case, admitted in October, 1960, a correct clinical diagnosis was made.…”

Section: Hospital Canadatmentioning

confidence: 99%

Myxoma of the Left Atrium

Anderson¹,

Aldridge²,

Greenwood³

1961

Heart

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Hospital, CanadatIn the past five years four patients with an atrial myxoma have been operated upon at the Toronto General Hospital. The clinical diagnosis in the first three cases (Aldridge and Greenwood, 1960) was mitral stenosis. In the fourth case, admitted in October, 1960, a correct clinical diagnosis was made.Case Report A woman, 40 years old, with no history of rheumatic fever, was well until 1957 when she developed an illness lasting six weeks that was probably pneumonia: recovery was complete. Before admission, she had noted fatigue for two years, exertional dyspncea for one year, and faintness on stooping for six months. There was no history of hTmoptysis, nocturnal dyspncea, arrhythmia, or embolism.The patient was in no distress. The skin was warm and without cyanosis. The pulse rate was 70 a minute, and was normal in volume and rhythm. The blood pressure was 110/60. The jugular venous pulse showed a and v waves of equal height, 2 cm. above the sternal angle with the patient at 30°. The first sound was palpable at the apex. There was a slight impulse palpable at the left sternal border. The second sound and left ventricle were not felt. The first sound was moderately loud while the second was normally split with slight accentuation of the pulmonary component. A grade II/IV rumbling mid-diastolic murmur without presystolic accentuation was localized near the lower left sternal border. A grade II/IV blowing, early and mid-systolic murmur was maximal in the third left interspace, and was conducted downwards along the sternal border. Both murmurs increased in intensity with normal expiration. No opening snap was heard. Change in position did not alter these findings.Phonocardiography demonstrated the systolic murmur, beginning with the first sound, but ending before the second. The diastolic murmur was not well recorded. No opening snap was seen.The lung fields were clear. There was no hepatomegaly or peripheral oedema. On radiological examination, there was no enlargement of the heart shadow. The hilar pulsations were normal. Moderate enlargement of the left atrium produced a double shadow at the right heart border and a prominence of the left heart border. No calcium was seen in either mitral or aortic valve areas. Kerley's lines were present. The cardio-thoracic ratio was 41 per cent.The electrocardiogram showed sinus rhythm, a P-R interval of 0-2 sec., a broad P wave in lead II, and S-T segment depression in keeping with digitalis therapy. The QRS complex did not suggest dominance of either ventricle.Several urine samples were normal. The hoemoglobin was 11-7 per 100 ml., white cell count 12,300; E.S.R. 44 mm./first hour; total and differential serum proteins by electrophoresis were normal.At right heart catheterization, the mean pulmonary "wedge" pressure was elevated to 26 mm. Hg, the mean pulmonary arterial pressure was 34 mm., and the mean right atrial pressure was 3 mm. The pulmonary "wedge" tracing showed a relatively high v wave and a rapid y descent (Fig. 1). The cardiac output by direct Fick...

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“…Three comprehensive retrospective reviews of atrial myxoma have recently appeared, dealing mainly with cases diagnosed for the first time at operation or at necropsy (Campeau and David, 1960;Aldridge and Greenwood, 1960;Differding et al, 1961). Campeau and David reported 65 myxomas (57 in the left atrium) collected over a period from January, 1954, to January, 1959 Aldridge and Greenwood published an analysis of 32 cases of left atrial myxoma reported in the literature, and added three of their own.…”

Section: Discussionmentioning

confidence: 99%