Myxomatous Mitral Valve Disease in Dogs - an Update and Perspectives

Petrič, Aleksandra Domanjko

doi:10.14432/j.macvetrev.2014.11.026

Cited by 10 publications

(18 citation statements)

References 36 publications

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“…Assessment of higher murmur in group B2 might be related to the progressive severity of the illnesses. It has been reported that the severity of DMVD in dogs was well associated with lower serum serotonin concentrations and higher LA/Ao which causes low serotonin concentrations (Ljungvall et al, 2014;Petric, 2015). The positive correlation between the cardiac auscultation (murmur) and LA/Ao (Table 3) can explain this result.…”

Section: Discussionmentioning

confidence: 75%

“…DMVD is the leading cause of cardiac disease in dogs throughout the world (Bonagura and Schober, 2009;Borgarelli et al, 2012;Terzo et al, 2009). Its prevalence has been found to be associated with breed, age and body size (Bernay et al, 2010;Borgarelli et al, 2004;Petric, 2015). Older small-breed dogs are predisposed (Petric, 2015).…”

Section: Introduction *Anatolianmentioning

confidence: 99%

“…Its prevalence has been found to be associated with breed, age and body size (Bernay et al, 2010;Borgarelli et al, 2004;Petric, 2015). Older small-breed dogs are predisposed (Petric, 2015). However, less is known about the disease prevalence in large breeds.…”

Section: Introduction *Anatolianmentioning

confidence: 99%

“…Jones and Zook (1965) reported that DMVD is an age dependent disease. Males predominated in most of the studies (Pedersen and Häggström, 2000;Serfass et al, 2006;Thrusfield et al, 1985;Petric, 2015).…”

Section: Introduction *Anatolianmentioning

confidence: 99%

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Clinical and cardiologic assessment of Anatolian shepherd dogs with asymptomatic degenerative mitral valve disease

al.¹

2019

Int. j. adv. appl. sci.

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Degenerative mitral valve disease (DMVD) is the leading cause of cardiac disease and heart failure in the dog. Advanced age, breed and male gender are well-known risk factors for DMVD. The incidence of the disease in German Shepherds seems to be noteworthy. Early diagnosis of DMVD is related to the identification of a left apical systolic murmur, characteristic of MR in a dog. Dogs with DMVD had a low frequency of arrhythmias compared to other cardiac conditions. The goal of the study was (i) to evaluate the age and gender incidences of the asymptomatic Anatolian Shepherd Dogs (ASHs) with DMVD and, (ii) to investigate the importance of its clinical, radiological, electrocardiographic (ECG) findings and the correlations of those with some echo cardio logical measurements. 35 healthy ASHs (control group) and 38 ASHs with DMVD (experimental group) were used as the materials. The severity of cardiac disease was classified according to the American College of Veterinary Internal Medicine (ACVIM) consensus statement. Thirty two dogs (84.2%) were males and 6 dogs (15.8%) were females in the experimental group. The median age, the intensity of heart murmur and the severity of mitral regurgitation (MR) of the B2 dogs were bigger (p <0.05) than that of the B1 dogs. There was a positive correlation (P<0.05) between age and mitral valve lesions (MVLs). The clinical examination assessed by cardiac auscultation (murmur) was not correlated to MVLs, VHS, ECG findings and ARJ/LAA (P>0.05). The intensity of murmur was correlated to left ventricle to aorta ratio (LA/Ao) and it was not correlated (P>0.05) to MVLs, vertebral heart scale (VHS), ECG findings and regurgitant jet area to LA area ratio (ARJ/LAA). The correlations between ECG findings and VHS, along with, LA/Ao and ARJ/LAA were positive (P <0.05). In conclusion, aging and male gender may have a significant impact on DMVD progression in ASHs. Assessment of higher murmur in group B2 might be related to the progressive severity of the illnesses. The prevalence of arrhythmia was low in asymptomatic ASHs with DMVD. P-mitrale was noteworthy.

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Section: Discussionmentioning

confidence: 75%

Section: Introduction *Anatolianmentioning

confidence: 99%

Section: Introduction *Anatolianmentioning

confidence: 99%

Section: Introduction *Anatolianmentioning

confidence: 99%

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Clinical and cardiologic assessment of Anatolian shepherd dogs with asymptomatic degenerative mitral valve disease

al.¹

2019

Int. j. adv. appl. sci.

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“…Systolic heart murmur presented in chest auscultation. Systolic murmur at the mitral area is one of the characteristics of MMVD, which increases in intensity as the disease progresses (Petric 2015). Figure 1 shows 2D echocardiographic B-mode results in this dog was thickening and prolapse of mitral valve.…”

Section: ■ Results and Discussionmentioning

confidence: 84%

Sonogram features of myxomatous mitral valve disease and abdominal organ dissorders in a senior mini pomeranian

Utami

Noviana

2019

ARSHI vet lett

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A 12-years-old mini pomeranian with clinical symptom of coughing was referred to Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Bogor Agricultural University for evaluation. The radiogram showed difus interstitial nodular pattern on the lungs and enlargement of the spleen. Abdominal ultrasonography and echocardiography was performed to further diagnose the dog. Abdominal ultrasonography was taken using linear probe with frequency 5-11 MHz. Echocardiography was perfomed with right parasternal and left apical views using microconvex probe, with frequency 6-8.8 MHz. Abdominal utrasonogram showed that the dog had billiary sludge, mild splenitis, nephrolithiasis, and urolithiasis. Two dimensional Brightness-mode echocardiography showed thickened and prolapsed mitral valve. Two-dimensional M-mode echocardiography showed increasing of left ventricle lumen dimension (LVID) at systole, decreasing of fractional shortening (FS), and enlargement of left atrial. Color Flow Doppler-mode revealed there was mild regurgitation at the mitral valve. These results lead diagnosis to dilated cardiomyopathy and myxomatous mitral valve disease

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Histopathological changes of pulmonary vascular remodeling in dogs affected with pulmonary hypertension secondary to degenerative mitral valve disease

Sakarin

Rungsipipat

Surachetpong

2021

Journal of Veterinary Cardiology

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Myxomatous Mitral Valve Disease in Dogs - an Update and Perspectives

Cited by 10 publications

References 36 publications

Clinical and cardiologic assessment of Anatolian shepherd dogs with asymptomatic degenerative mitral valve disease

Clinical and cardiologic assessment of Anatolian shepherd dogs with asymptomatic degenerative mitral valve disease

Sonogram features of myxomatous mitral valve disease and abdominal organ dissorders in a senior mini pomeranian

Histopathological changes of pulmonary vascular remodeling in dogs affected with pulmonary hypertension secondary to degenerative mitral valve disease

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