N-acetylcysteine amide and di- N-acetylcysteine amide protect retinal cells in culture via an antioxidant action

Wood, John P.M.; Chidlow, Glyn; Wall, G. Michael; Casson, Robert J.

doi:10.1016/j.exer.2024.110074

Experimental Eye Research

2024

DOI: 10.1016/j.exer.2024.110074

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N-acetylcysteine amide and di- N-acetylcysteine amide protect retinal cells in culture via an antioxidant action

John P.M. Wood,

Glyn Chidlow,

G. Michael Wall

et al.

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2024

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Cited by 1 publication

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Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs

Duncan,

Bowman,

Laster

et al. 2024

Trans. Vis. Sci. Tech.

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Inherited retinal degeneration (IRD) disease and age-related macular degeneration (AMD) are leading causes of irreversible vision loss and blindness. Although significant progress has advanced the field in the past 5 years, significant challenges remain. The current article reviews the accomplishments and research advances that have fueled the development of treatments for patients with IRD and AMD, including the first approved gene-augmentation treatment for RPE65- related retinal degeneration and complement inhibition therapies to slow progression of geographic atrophy (GA) in AMD. The article outlines opportunities to address gaps and unmet needs that should lead to additional progress toward the development of treatments for patients with IRDs and non-neovascular AMD in the future.

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Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs

Duncan,

Bowman,

Laster

et al. 2024

Trans. Vis. Sci. Tech.

View full text Add to dashboard Cite

show abstract

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N-acetylcysteine amide and di- N-acetylcysteine amide protect retinal cells in culture via an antioxidant action

Cited by 1 publication

References 92 publications

Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs

Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs

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