N-chlorodifluoromethylenimine, CF₂NCl

Abstract

Summarjr The simplest N-chloroperfluoroalkylenimine, CF,=NCl, has been synthesised for the first time by thermolysis of the previously unknown NN-dichloroperhalogeno-alkylamine CF,Cl-NCl,.ALTHOUGH higher N-chloroperfluoroalkylenimines have been reported,IS2 and isomers of CF,=NCl are known,%* the synthesis of this simplest N-chloroperfluoroalkylenimine was not accomplished until this work. In a novel dechlorination reaction, the new compound was isolated ( >SO%) from the thermolysis of CF,Cl*NCl,.

A facile synthesis of unsymmetrical ureas

“…To our knowledge, this method for the preparation of 5 has not been published. Alternative routes to 5 involve insertion of carbon monoxide into trifluoroethyl hypochlorite 16 and cleavage of O-trifluoroethyl-S-ethyl carbonochloridothioate with sulfuryl chloride. 17 Applying our method compound 5 was synthesized in multigram quantities and purified by distillation.…”

Hepatocellular carcinoma: From bedside to proteomics

“…Since its first publication there was a tremendous upsurge of interest and the realization of the potential of the applications of 2-DE in clinical laboratories. This was summarized by two special issues of Clinical Chemistry [38,39] and a monograph [40]. Since then, numerous advances have been made in 2-DE technologies, including the introduction of IPG in the first dimension [41] which was later to become one of the main technology platforms in the current field of proteomics [42][43][44].…”

Examples of interesting non-metal compounds derived from elemental fluorine

“…The interesting N-chloroimine F 2 C = NCl was isolated by Fox and coworkers by reaction of cyanogen chloride with chlorine monofluoride, followed by dechlorination with mercury [23]:…”