NADPH-diaphorase-, Nitric Oxide Synthase- and VIP-Containing Nerve Structures in the Hen Oviduct: A Histochemical and Immunohistochemical Study.

Costagliola, Anna; Mayer, Bernd; Vittoria, Alfredo; Carrese, E; Lamanna, Claudia; Cecio, A

doi:10.1679/aohc.60.245

Cited by 21 publications

(15 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although Costagliola et al (1997) observed neurones and nerve fibres in the oviductal mucosa, the present study is the first to report ganglia with more than three neurones in the tunica mucosa of the oviduct, specifically in the uterovaginal junction. Costagliola et al (1997) and Biswal (1954) did not specify whether the fibres extended into the plicae and did not report on the innervation of the uterovaginal junction. However, Costagliola et al (1997) suggested that mucosal neurones in the vagina frequently had a long axon.…”

Section: Discussioncontrasting

confidence: 50%

“…Other nerve fibres may have originated from the neurones contained in the tunica muscularis (Biswal, 1954;Gilbert and Lake, 1963;Costagliola et al, 1997) or neurones in peripheral ganglia on the exterior surface of the caudal oviduct (Freedman and Sturkie, 1963;Gilbert and Lake, 1963). It is also possible that afferent fibres originated from lumbosacral dorsal root ganglia.…”

Section: Discussionmentioning

confidence: 99%

“…It is also possible that afferent fibres originated from lumbosacral dorsal root ganglia. Biswal (1954) and Costagliola et al (1997) documented the presence of small ganglia containing one to three neurones in the tunica muscularis of the chicken vagina. Although Costagliola et al (1997) observed neurones and nerve fibres in the oviductal mucosa, the present study is the first to report ganglia with more than three neurones in the tunica mucosa of the oviduct, specifically in the uterovaginal junction.…”

Section: Discussionmentioning

confidence: 99%

“…Biswal (1954) and Costagliola et al (1997) documented the presence of small ganglia containing one to three neurones in the tunica muscularis of the chicken vagina. Although Costagliola et al (1997) observed neurones and nerve fibres in the oviductal mucosa, the present study is the first to report ganglia with more than three neurones in the tunica mucosa of the oviduct, specifically in the uterovaginal junction. Costagliola et al (1997) and Biswal (1954) did not specify whether the fibres extended into the plicae and did not report on the innervation of the uterovaginal junction.…”

Section: Discussionmentioning

confidence: 99%

“…Costagliola et al (1997) and Biswal (1954) did not specify whether the fibres extended into the plicae and did not report on the innervation of the uterovaginal junction. However, Costagliola et al (1997) suggested that mucosal neurones in the vagina frequently had a long axon. If this observation is correct, the mucosal neurones in the uterovaginal junction represent a possible source of the fibres that innervate the sperm storage tubules.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Evidence for the innervation of sperm storage tubules in the oviduct of the turkey (Meleagris gallopavo)

Freedman¹

2001

Reproduction

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 50%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Evidence for the innervation of sperm storage tubules in the oviduct of the turkey (Meleagris gallopavo)

Freedman¹

2001

Reproduction

View full text Add to dashboard Cite

Peripheral and Central Neural Bases of Orgasm

Jannini¹,

Wise²,

Frangos³

et al. 2018

Textbook of Female Sexual Function and Dysfunction

View full text Add to dashboard Cite

Morphological and neurochemical differences in peptidergic nerve fibers of the mouse vagina

Barry

Sharma

et al. 2017

J of Comparative Neurology

View full text Add to dashboard Cite

The vagina is innervated by a complex arrangement of sensory, sympathetic, and parasympathetic nerve fibers that contain classical transmitters plus an array of neuropeptides and enzymes known to regulate diverse processes including blood flow and nociception. The neurochemical characteristics and distributions of peptide-containing nerves in the mouse vagina are unknown. This study used multiple labeling immunohistochemistry, confocal maging and analysis to investigate the presence and colocalization of the peptides vasoactive intestinal polypeptide (VIP), calcitonin-gene related peptide (CGRP), substance P (SP), neuropeptide tyrosine (NPY), and the nitric oxide synthesizing enzyme neuronal nitric oxide synthase (nNOS) in nerve fibers of the murine vaginal wall. We compared cervical and vulvar areas of the vagina in young nullipara and older multipara C57Bl/6 mice, and identified differences including that small ganglia were restricted to cervical segments, epithelial fibers were mainly present in vulvar segments and most nerve fibers were found in the lamina propria of the cervical region of the vagina, where a higher number of fibers containing immunoreactivity for VIP, CGRP, SP, or nNOS were found. Two populations of VIP-containing fibers were identified: fibers containing CGRP and fibers containing VIP but not CGRP. Differences between young and older mice were present in multiple layers of the vaginal wall, with older mice showing overall loss of innervation of epithelium of the proximal vagina and reduced proportions of VIP, CGRP, and SP containing nerve fibers in the distal epithelium. The distal vagina also showed increased vascularization and perivascular fibers containing NPY. Immunolabeling of ganglia associated with the vagina indicated the likely origin of some peptidergic fibers. Our results reveal regional differences and age- or parity-related changes in innervation of the mouse vagina, effecting the distribution of neuropeptides with diverse roles in function of the female genital tract.

show abstract

NADPH-diaphorase-, Nitric Oxide Synthase- and VIP-Containing Nerve Structures in the Hen Oviduct: A Histochemical and Immunohistochemical Study.

Cited by 21 publications

References 44 publications

Evidence for the innervation of sperm storage tubules in the oviduct of the turkey (Meleagris gallopavo)

Evidence for the innervation of sperm storage tubules in the oviduct of the turkey (Meleagris gallopavo)

Peripheral and Central Neural Bases of Orgasm

Morphological and neurochemical differences in peptidergic nerve fibers of the mouse vagina

Contact Info

Product

Resources

About