Nailfold capillaroscopy in systemic sclerosis: Is there any difference between videocapillaroscopy and dermatoscopy?

Doğan, Sibel; Akdoğan, Ali; Atakan, Nilgün

doi:10.1111/srt.12067

Cited by 25 publications

(21 citation statements)

References 13 publications

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“…The training needed for the device is minimal (∼5 days ) and the required examination time is short (∼10 minutes including image recording). An NVC apparatus is more costly than handheld devices such as dermatoscopes, but NVC has been shown to permit more‐detailed assessments and the grading of more images . During patient follow‐up, detailed assessment and quantification of abnormalities is important, and therefore, handheld tools may not be as useful in this setting .…”

Section: Discussionmentioning

confidence: 99%

Nailfold Videocapillaroscopic Features and Other Clinical Risk Factors for Digital Ulcers in Systemic Sclerosis: A Multicenter, Prospective Cohort Study

Chadha‐Boreham

Cottreel

Pfister

et al. 2016

Arthritis & Rheumatology

130

118

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ObjectiveTo identify nailfold videocapillaroscopic features and other clinical risk factors for new digital ulcers (DUs) during a 6‐month period in patients with systemic sclerosis (SSc).MethodsIn this multicenter, prospective, observational cohort study, the videoCAPillaroscopy (CAP) study, we evaluated 623 patients with SSc from 59 centers (14 countries). Patients were stratified into 2 groups: a DU history group and a no DU history group. At enrollment, patients underwent detailed nailfold videocapillaroscopic evaluation and assessment of demographic characteristics, DU status, and clinical and SSc characteristics. Risk factors for developing new DUs were assessed using univariable and multivariable logistic regression (MLR) analyses.ResultsOf the 468 patients in the DU history group (mean ± SD age 54.0 ± 13.7 years), 79.5% were female, 59.8% had limited cutaneous SSc, and 22% developed a new DU during follow‐up. The strongest risk factors for new DUs identified by MLR in the DU history group included the mean number of capillaries per millimeter in the middle finger of the dominant hand, the number of DUs (categorized as 0, 1, 2, or ≥3), and the presence of critical digital ischemia. The receiver operating characteristic (ROC) of the area under the curve (AUC) of the final MLR model was 0.738 (95% confidence interval [95% CI] 0.681–0.795). Internal validation through bootstrap generated a ROC AUC of 0.633 (95% CI 0.510–0.756).ConclusionThis international prospective study, which included detailed nailfold videocapillaroscopic evaluation and extensive clinical characterization of patients with SSc, identified the mean number of capillaries per millimeter in the middle finger of the dominant hand, the number of DUs at enrollment, and the presence of critical digital ischemia at enrollment as risk factors for the development of new DUs.

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Section: Discussionmentioning

confidence: 99%

Nailfold Videocapillaroscopic Features and Other Clinical Risk Factors for Digital Ulcers in Systemic Sclerosis: A Multicenter, Prospective Cohort Study

Chadha‐Boreham

Cottreel

Pfister

et al. 2016

Arthritis & Rheumatology

130

118

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“…Fortuitously, there are a number of low cost and handheld devices such as dermatoscopes and ophthalmoscopes which achieve a good visualisation of the nailfolds at around 10-20-fold magnification (see Figure 2c). A number of studies directly comparing these techniques with WSM and NVC have found a reassuring concordance [10][11][12]. In particular, although the rate of "unclassifiable" images is higher, ample diagnostically relevant findings can be elicited, even if more subtle changes can be missed.…”

Section: Handheld Devices-ophthalmoscopes Dermatoscopes Usb Microscmentioning

confidence: 90%

The Established and Evolving Role of Nailfold Capillaroscopy in Connective-Tissue Disease

Parker¹,

McGill²

2020

Connective Tissue Disease - Current State of the Art

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Nailfold capillaroscopy (NFC) is a low-cost, non-invasive, rapid, highly specific and reproducible investigation well established in the diagnosis of systemic sclerosis and related conditions. This chapter will detail the relevant underlying scientific principles that underpin the investigation, the methods for performing NFC, the range of abnormalities that can be present and the currently available classification criteria before moving on to discuss the various established and emerging applications as relevant to the connective tissue diseases. In addition to its role in the diagnosis of SSc, highlighted by its inclusion in the most recent ACR/EULAR consensus classification criteria, NFC has been shown to predict disease activity, many organ-specific complications such as digital ulcers, pulmonary hypertension and interstitial lung disease, and even mortality. It is emerging as a useful investigation in other CTDs characterised by microvasculopathy, such as in the idiopathic inflammatory myopathies and mixed connective tissue disease, as well as being studied as a serial investigation in patients to act as a potential biomarker and measure of treatment efficacy. NFC can contribute to the earlier identification of patients with CTDs with clinically important complications and if applied accurately, therefore, can help improve outcomes in these often challenging diseases.

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“…Dogan et al . compared the diagnostic value of dermoscopy and videocapillaroscopy for determining nailfold capillary pattern changes in patients with SSc, and concluded that dermoscopy was efficient in recognizing the pathognomonic changes …”

Section: Discussionmentioning

confidence: 99%

“…7 Dogan et al compared the diagnostic value of dermoscopy and videocapillaroscopy for determining nailfold capillary pattern changes in patients with SSc, and concluded that dermoscopy was efficient in recognizing the pathognomonic changes. 24 We used a videodermatoscope with 9 30 magnification, and easily recognized the nailfold capillary changes in patients with BD, thus we recommend videodermoscopy for evaluating such changes. However, NVC can only evaluate most features of capillary morphology qualitatively, except for capillary density, which could be measured quantitatively.…”

Section: Discussionmentioning

confidence: 99%

Nailfold capillaroscopy in Behçet disease, performed using videodermoscopy

et al. 2014

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Nailfold capillaroscopy in systemic sclerosis: Is there any difference between videocapillaroscopy and dermatoscopy?

Abstract: We suggest that dermatoscopy is efficient enough to identify pathognomonic changes in NCP in SSc as well as VCAP and find dermatoscopy as a very easy applicable and convenient method than VCAP although VCAP facilitates a more detailed evaluation of NCP.

Cited by 25 publications

References 13 publications

Nailfold Videocapillaroscopic Features and Other Clinical Risk Factors for Digital Ulcers in Systemic Sclerosis: A Multicenter, Prospective Cohort Study

Nailfold Videocapillaroscopic Features and Other Clinical Risk Factors for Digital Ulcers in Systemic Sclerosis: A Multicenter, Prospective Cohort Study

The Established and Evolving Role of Nailfold Capillaroscopy in Connective-Tissue Disease

Nailfold capillaroscopy in Behçet disease, performed using videodermoscopy

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