Naja naja cobra bite

Britt, Andres M.; Burkhart, Keith

doi:10.1016/s0735-6757(97)90202-3

Cited by 19 publications

(14 citation statements)

References 15 publications

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“…The mainstay of treatment for cobra envenomation is aggressive supportive care (mechanical ventilation and hemodynamic support) and the administration of antivenom (27). Of 12 patients bitten by Naja atra, only one did not receive antivenom therapy because of absence of envenomation.…”

Section: Discussionmentioning

confidence: 99%

“…However, five patients needed surgical intervention subsequently despite an antivenom dose higher than those given to patients not requiring surgery. Although the use of antivenom is indicated for systemic manifestations of envenomation such as the development of neurotoxicity or cardiotoxicity, the question of whether the increased dosage or early administration of antivenom for Naja atra bites is beneficial for preventing not only the abovementioned systemic reaction but also tissue injuries requires further study (27,28).…”

Section: Discussionmentioning

confidence: 99%

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Venomous snakebites and antivenom treatment according to a protocol for pediatric patients in taiwan

Wang¹,

Tsan²,

Mao³

et al. 2009

J. Venom. Anim. Toxins incl. Trop. Dis

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and adolescents, with a median age of 9.9 years (ranging from 2 to 18 years), was identified.Forty-five patients (82%) were bitten between May and September. Thirty-five patients (64%) received antivenom therapy, 28 of them (80%) within two hours after being bitten. No fatalities occurred and only five of 35 patients (14%) had major morbidity when treated according to the protocol. Thirty-one snakes (56%) were identified and 12 of them (38%) were Naja atra. This study indicates that a protocol for children affected by snakebites is valuable for guiding emergency physicians to treat these patients immediately. Further strategies are required to reduce the morbidity rate that occurs as a result of Naja atra bite.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Venomous snakebites and antivenom treatment according to a protocol for pediatric patients in taiwan

Wang¹,

Tsan²,

Mao³

et al. 2009

J. Venom. Anim. Toxins incl. Trop. Dis

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“…In Malaysia, the common cobra (Naja kaouthia) is responsible for most bites, which display varied clinical pictures, the most prominent one being neurotoxicity (2). In some cases, the bites produce significant local swelling and extensive tissue necrosis that may lead to the development of long term complications, such as chronic ulceration, infection and osteomyelitis (3).…”

Section: Introductionmentioning

confidence: 99%

“…However, antivenom does not provide enough protection against some toxic enzyme effects induced by snake venoms (4). Antivenom treatment, in some cases, is not be able to prevent local tissue necrosis and may also predispose the victim to the risk of hypersensitivity reactions such as anaphylaxis and serum sickness due to equine and ovine allergens present in the serum (2,5).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of tannins from Mimosa pudica and tannic acid in neutralizing cobra (Naja kaouthia) venom

Sia¹,

Vejayan²,

Jamuna³

et al. 2011

J. Venom. Anim. Toxins incl. Trop. Dis

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Abstract:In the present study, the effectiveness of Mimosa pudica tannins (MPT) in neutralizing the lethality of Naja kaouthia venom was compared with commercially derived tannins. Preincubation of MPT with N. kaouthia venom maintained 100% survival of mice after 24 hours. The mouse group in which there was no preincubation, no protection against the effects of the venom was observed. M. pudica tannin was found to be more effective in neutralizing the lethality of N. kaouthia venom when compared to commercial tannic acid. Two protein spots were missing in the two-dimensional gel electrophoresis (2-DE) of the MPT treated mouse indicating the down-regulation of venom proteins. The results from this study indicated that tannins obtained from M. pudica are better than tannic acid in neutralizing the lethality of N. kaouthia venom in vitro. However, further investigations are required to establish that M. pudica has potential for treating N. kaouthia snakebites.

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“…According to Government of India data, there were 61,507 snake bites with mortality of 1124 in 2006; 76,948 bites and 1359 deaths in 2007. A high mortality of 50,000 deaths each year has also been published [3] . In the state of Maharashtra an average of 1,224 deaths per year (2.43 deaths per 1,00,000 per year) were reported between 1974 and 1978.…”

Section: Introductionmentioning

confidence: 99%