Name agreement, frequency and age of acquisition, but not grammatical class, affect object and action naming in Spanish speaking participants with Alzheimer's disease

Rodríguez‐Ferreiro, Javier; Davies, Robert; González-Nosti, María; Barbón, Analía; Cuetos, Fernando

doi:10.1016/j.jneuroling.2008.05.003

Cited by 38 publications

(61 citation statements)

References 61 publications

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“…Hence, significant differences between the experimental and control groups were observed in all the tasks except for the pseudoword and text dictation tests. The oral language impairment of AD patients reported in previous studies González Nosti et al, 2008;Rodríguez-Ferreiro et al, 2009) was also present in our participants, according to their impaired results in the control oral naming task. Furthermore, this deficit appeared to extend also into the written language domain, as evidenced by significantly poorer scores obtained by the AD group in the written naming test.…”

Section: Discussionsupporting

confidence: 86%

“…However, a linguistic deficit is also present in many of the cases. The verbal output of AD patients, even in the early stages of the disease, lacks lexical diversity and presents semantic errors and circumlocutions (Cuetos, Rodríguez-Ferreiro, & Menéndez, 2009;Cuetos, Rodríguez-Ferreiro, Sage, & Ellis, 2012;González Nosti, Rodríguez Ferreiro, & Cuetos Vega, 2008;Rodríguez-Ferreiro, Davies, González-Nosti, Barbón, & Cuetos, 2009). This linguistic pattern has been extensively documented in the oral domain, but there is much less evidence regarding writing abilities of these patients (for a review see Neils-Strunjas, GrovesWright, Mashima, & Harnish, 2006).…”

Section: Introductionmentioning

confidence: 99%

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Neural correlates of spelling difficulties in Alzheimer’s disease

et al. 2014

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Abstract.Alzheimer's disease (AD) is associated with a general cognitive decline that affects the memory and language domains. Thus, an oral production deficit with a lexical-semantic origin has been widely observed in these patients. Their written production capacities, however, have been much less studied. We assessed the spelling abilities of 22 AD patients and a group of matched healthy controls with a test battery including written picture naming and word and pseudoword dictation tests, as well as text dictation and spontaneous writing tasks. The results of the AD patients in the discriminative tasks were then entered into voxel-based morphometry analyses along with their grey matter volumes. The patient group presented a selective impairment for word dictation, which contrasted with a spared capacity to spell pseudowords, and showed more difficulties for words with arbitrary and rule-based orthography. Moreover, they also produced less complete syntactic units in the spontaneous writing task. These results point out the lexical-semantic, as opposed to sublexical, nature of the spelling deficit associated to AD. In addition, we recognized a mainly left-lateralized cortical network, including areas in the posterior inferior temporal lobe and the superior region of the parietal cortex, which might be responsible for this impairment. Other regions, such as the putamen, were also associated to the deficit. The results of this study, hence, improve our understanding of the neuropsychological and neuroanatomical mechanisms that underlie the cognitive symptoms associated to AD.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Neural correlates of spelling difficulties in Alzheimer’s disease

et al. 2014

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“…Overall, these theories highlight that word processing can be affected at three relatively distinct stages: during lexical selection, during lemma activation, or when activating the (morpho-)phonological word forms, but the level of breakdown is not always immediately apparent. Moreover, key psycholinguistic variables (e.g., lexical frequency, age of acquisition, imageability, picture complexity, syllable length) may exert a stronger influence than grammatical class per se on action and object retrieval performances in adults with acquired naming impairments (Druks et al, 2006;Rodriguez-Ferreiro, Davies, Gonzalez-Nosti, Barbon, & Cuetos, 2009).…”

Section: Introductionmentioning

confidence: 99%

Action and object naming in schizophrenia

Kambanaros

Messinis

Georgiou

et al. 2010

Journal of Clinical and Experimental Neuropsychology

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Patients with schizophrenia demonstrate impaired action verbal fluency, but no study has examined verb-noun differences using picture naming. The present study compared object and action naming in 20 adult patients diagnosed with schizophrenia (DSM-IV-TR, Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, Text Revision; American Psychiatric Association, 2000) criteria, and 20 demographically matched healthy controls, using pictures. Overall, schizophrenic patients showed poorer naming than controls on all measures of object and action lexical semantic access and retrieval despite normal comprehension for action and object names. Results further indicated that action names were significantly more difficult to retrieve than object names in schizophrenic patients. The absence of dissociation in comprehension of action and object names but semantic errors in naming both classes suggests intact conceptual-semantic stores among middle-aged community-dwelling outpatients with schizophrenia but difficulties mapping semantics onto the lexicon. Action-naming impairments can arise from both semantic and postsemantic origins in schizophrenia. These results have implications for the neurobiology of language given the association between both schizophrenia and verb processing and frontal damage. Moreover, the issue being addressed is important for a cognitive characterization of schizophrenia and for an understanding of the representations of action and object names in the brain.

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“…memory, motor control, use of language, etc. For example, loss of vocabulary is a common symptom of dementia [18], [20], and this may be discoverable by text mining if (e.g.) the user uses e-mail or social networks to keep in touch with kin.…”

Section: Samsmentioning

confidence: 99%

Discovering affect-laden requirements to achieve system acceptance

Sutcliffe

Rayson

Bull

et al. 2014

2014 IEEE 22nd International Requirements Engineering Conference (RE)

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Abstract-Novel envisioned systems face the risk of rejection by their target user community and the requirements engineer must be sensitive to the factors that will determine acceptance or rejection. Conventionally, technology acceptance is determined by perceived usefulness and ease-of-use, but in some domains other factors play an important role. In healthcare systems, particularly, ethical and emotional factors can be crucial. In this paper we describe an approach to requirements discovery that we developed for such systems. We describe how we have applied our approach to a novel system to passively monitor users for signs of cognitive decline consistent with the onset of dementia. A key challenge was eliciting users' reactions to emotionally charged events never before experienced by them at first hand. Our goal was to understand the range of users' emotional responses and their values and motivations, and from these formulate requirements that would maximise the likelihood of acceptance of the system. The problem was heightened by the fact that the key stakeholders were elderly people who represent a poorly studied user constituency. We discuss the elicitation and analysis methodologies used, and our experience with tool support. We conclude by reflecting on the affect issues for RE and for technology acceptance.

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Name agreement, frequency and age of acquisition, but not grammatical class, affect object and action naming in Spanish speaking participants with Alzheimer's disease

Cited by 38 publications

References 61 publications

Neural correlates of spelling difficulties in Alzheimer’s disease

Neural correlates of spelling difficulties in Alzheimer’s disease

Action and object naming in schizophrenia

Discovering affect-laden requirements to achieve system acceptance

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