Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescence

Liu, Changjun; Zhang, Peng; Zhai, Xinyun; Tian, Faming; Li, Wenchen; Yang, Jianhai; Liu, Yuan; Wang, Hongbo; Wang, Wei; Liu, Wenguang

doi:10.1016/j.biomaterials.2012.01.052

Cited by 695 publications

(526 citation statements)

References 31 publications

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“…This is because of the fact that this microscopy-based technique has large potential in leading to 4 Journal of Nanomaterials [86]. (B) XRD pattern of C-dots from neutralization heating of glucose [28].…”

Section: Scanning Probe Microscopiesmentioning

confidence: 99%

“…When the X-rays interacts with a crystallite C-dots sample, the constructive interference is produced, and these diffracted X-rays are then detected, processed, and counted, revealing the average structure of C-dots [86,87,89,[130][131][132][133][134][135][136]. Figure 3(A) displays a typical XRD pattern of polyethylenimine (PEI) functionalized C-dots (C-dots-PEI) derived from microwave-assisted pyrolysis of glycerol in the presence of branched PEI [86]. In addition, XRD also provides the information about the purity of an as-synthesized C-dots sample.…”

Section: X-ray Diffractionmentioning

confidence: 99%

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Characterization and Analytical Separation of Fluorescent Carbon Nanodots

Gong

Liu

et al. 2017

Journal of Nanomaterials

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Carbon nanodots (C-dots) are recently discovered fluorescent carbon nanoparticles with typical sizes of <10 nm. The C-dots have been reported to have excellent photophysical and chemical characteristics. In recent years, the advances in the development and improvement in C-dots synthesis, characterization, and applications are burgeoning. In this review, we introduce the most commonly used techniques for the characterization of C-dots. The characterization techniques for C-dots are briefly classified, described, and illustrated with applied examples. In addition, the analytical separation methods for C-dots (including electrophoresis, chromatography, density gradient centrifugation, differential centrifugation, solvent extraction, and dialysis) are included and discussed according to their analytical characteristics. The review concludes with an outlook towards the future developments in the characterization and the analytical separation of C-dots. The comprehensive overview of the characterization and the analytical separation techniques will safeguard people to use each technique more wisely.

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Section: Scanning Probe Microscopiesmentioning

confidence: 99%

Section: X-ray Diffractionmentioning

confidence: 99%

Characterization and Analytical Separation of Fluorescent Carbon Nanodots

Gong

Liu

et al. 2017

Journal of Nanomaterials

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“…Furthermore, the superior biological properties of such carbon "nanolights" in terms of low toxicity and good biocompatibility in biological systems makes them a good alternative to SQDs, suggesting potential applications in bioimaging [5][6][7], biomolecule delivery but also in analytical (bio)sensing. In fact, most analytical applications are focused on techniques related to metal ion sensing.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent carbon quantum dot hydrogels for direct determination of silver ions

Cayuela

Soriano

Kennedy

et al. 2016

Talanta

115

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Citation for published item:gyuelD engelin nd orinoD wF vur nd uennedyD turt F nd teedD tF F nd l¡ relD wF @PHITA 9pluoresent ron quntum dot hydrogels for diret determintion of silver ionsF9D lntFD ISI F ppF IHHEIHSF Further information on publisher's website: Use policyThe full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. ABSTRACTThe paper reports for the first time the direct determination of silver ion (Ag + ) using luminescent Carbon Quantum Dot hydrogels (CQDGs). Carbon Quantum Dots (CQDs) with different superficial moieties (passivate-CQDs with carboxylic groups, thiol-CQDs and amine-CQDs) were used to prepare hybrid gels using a low molecular weight hydrogelator (LMWG). The use of the gels results in considerable fluorescence enhancement and also markedly influences selectivity. The most selective CQDG system for Ag + ion detection proved to be those containing carboxylic groups onto their surface. The selectivity towards Ag + ions is possibly due to its flexible coordination sphere compared with other metal ions.This fluorescent sensing platform is based on the strong Ag-O interaction which can quench the photoluminescence of passivate-CQDs (p-CQDs) through charge transfer. The limit of detection (LOD) and quantification (LOQ) of the proposed method were 0.55 and 1.83 µg·mL -1 , respectively, being applied in river water samples.

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“…Carbon nanomaterials including carbon nanotubes, nanoparticles, nanofibers, graphene oxide and carbon dots (C-dots), have attracted great attention due to their wide applications in solar cells [1], bioimaging [2], photocatalysts [3], nanoelectronic devices [4], photodynamic therapy [5] and gene delivery [6]. Among them, carbon dots are a new class of functional nanomaterials exhibiting their inherently unique photoluminescent properties, such as wavelengthtuneable emission, excellent solubility, good biocompatibility and chemical inertion [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%