Nano-composite of Co<sub>3</sub>O<sub>4</sub>and Cu with enhanced stability and catalytic performance for non-enzymatic electrochemical glucose sensors

Lin, Xiaoyun; Wang, Yanfang; He, Wenhui; Ni, Yongnian; Kokot, Serge

doi:10.1039/c7ra11540g

Cited by 11 publications

(3 citation statements)

References 46 publications

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“…A linear range from 2 μM to 2.11 mM was obtained with a detection limit of 0.085 μM (S/N = 3). The Co 3 O 4 nanoparticles with a size of about 15 nm were synthesized by solvothermal method for enzyme-free glucose detection [129]. The prepared powder was adhered to the Pt electrode, followed by the incorporation of spherical Cu nanoparticles.…”

Section: Other Metal/metal Oxide Composite-based Electrodementioning

confidence: 99%

Metal oxide-based composite for non-enzymatic glucose sensors

Liu

Zeng

Guo

et al. 2020

J Mater Sci: Mater Electron

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The increasing demand for monitoring the glucose concentration in the blood of diabetic patients has aroused the attention of researchers to prepare high-performance glucose biosensors. After decades of development, enzyme-based biosensors have gradually matured and commercialized, but they still suffer from insufficient stability due to the inherent defects of the enzyme. Non-enzymatic glucose sensor was proposed to address this issue. The introduction of nanotechnology has provided more possibilities for the preparation of highly efficient catalytic materials. Among the synthesized electrocatalysts, metal oxides are one of the most important components owing to their outstanding properties. Recent studies have integrated metal oxides with other materials to further improve sensor performance. This review focuses on the application of metal oxide-based hybrid structure in the glucose sensor, mainly including metal oxide/metal oxide, metal/metal oxide, and carbon material/metal oxide. The preparation method, electrochemical properties, and catalytic mechanism of the sensors are discussed in detail. Finally, we present some of the existing challenges and make personal predictions for the future development of non-enzymatic glucose sensors.

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Section: Other Metal/metal Oxide Composite-based Electrodementioning

confidence: 99%

Metal oxide-based composite for non-enzymatic glucose sensors

Liu

Zeng

Guo

et al. 2020

J Mater Sci: Mater Electron

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“…Transition metals are low cost and can be used as electrocatalytic materials for glucose. There are many electrocatalysts reported for transition metals, including pure metals [6,25], bimetals [7,26,27,28], compounds [29,30,31,32], and composites [33,34,35,36,37,38,39,40,41,42,43,44] for non-enzymatic glucose sensors. The catalytic principle of non-enzymatic glucose sensors based on transition metals is by using the d-electron of d-orbital to form medium-strength bonds with substrates, so that the analyte can be easily adsorbed at any time, and its products can be easily desorbed [3].…”

Section: Introductionmentioning

confidence: 99%

Facile Non-Enzymatic Electrochemical Sensing for Glucose Based on Cu2O–BSA Nanoparticles Modified GCE

Dai

Yang

Bao

et al. 2019

Sensors

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Transition-metal nanomaterials are very important to non-enzymatic glucose sensing because of their excellent electrocatalytic ability, good selectivity, the fact that they are not easily interfered with by chloride ion (Cl−), and low cost. However, the linear detection range needs to be expanded. In this paper, Cu2O–bovine serum albumin (BSA) core-shell nanoparticles (NPs) were synthesized for the first time in air at room temperature by a facile and green route. The structure and morphology of Cu2O–BSA NPs were characterized. The as-prepared Cu2O–BSA NPs were used to modify the glassy carbon electrode (GCE) in a Nafion matrix. By using cyclic voltammetry (CV), the influence from scanning speed, concentration of NaOH, and load of Cu2O–BSA NPs for the modified electrodes was probed. Cu2O–BSA NPs showed direct electrocatalytic activity for the oxidation of glucose in 50 mM NaOH solution at 0.6 V. The chronoamperometry result showed this constructing sensor in the detection of glucose with a lowest detection limit of 0.4 μM, a linear detection range up to 10 mM, a high sensitivity of 1144.81 μAmM−1cm−2 and reliable anti-interference property to Cl−, uric acid (UA), ascorbic acid (AA), and acetaminophen (AP). Cu2O–BSA NPs are promising nanostructures for the fabrication of non-enzymatic glucose electrochemical sensing devices.

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“…This can be attributed to the properties nanocomposites that have large surface area that support large numbers of electroactive substances and thus significantly improving proton and electron transfer. 172 The molecular imprinted polymer would also bring additional sensitivity and selectivity to the non-enzymatic sensor.…”

Section: Performance Analysismentioning

confidence: 99%

Review-Enzymatic and Non-Enzymatic Electrochemical Sensor for Lactate Detection in Human Biofluids

Shakhih

Rosslan

Noor

et al. 2021

J. Electrochem. Soc.

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Lactate is one of the potential biomarkers for assessing the human condition in clinical medicine or sports application. Lactate measurement could help in alerting various emergency conditions, such as bleeding, hypoxia, respiratory failure, and sepsis. Lactate monitoring could also benefit athletes in monitoring their muscle activity to prevent injury due to excessive muscle use or fatigue. In light of this, biosensor technology has been widely explored, especially on the use of electrochemical sensors to analyze the content of biological samples through direct biological activities conversion to electronic signals. This has become imperative for the detection of lactate which offers easy, quick, and reliable measurement. Despite enzymatic sensors being the focus of many studies, the non-enzymatic sensor has started to gain attention in recent years to overcome the stability issue of enzymes. This review presents an overview of the concepts, applications, and recent advancements of different electrochemical lactate sensors. A comparison of recent studies for both enzymatic and non-enzymatic lactate sensors based on electrode modification, enzymes, enzymes immobilizer, and several performance factors, including sensitivity, linearity, detection limit, and storage stability, all of which have been performed. Towards the end, this review also highlights some recommendations for future development of lactate sensors.

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Nano-composite of Co₃O₄and Cu with enhanced stability and catalytic performance for non-enzymatic electrochemical glucose sensors

Cited by 11 publications

References 46 publications

Metal oxide-based composite for non-enzymatic glucose sensors

Metal oxide-based composite for non-enzymatic glucose sensors

Facile Non-Enzymatic Electrochemical Sensing for Glucose Based on Cu2O–BSA Nanoparticles Modified GCE

Review-Enzymatic and Non-Enzymatic Electrochemical Sensor for Lactate Detection in Human Biofluids

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Nano-composite of Co3O4and Cu with enhanced stability and catalytic performance for non-enzymatic electrochemical glucose sensors

Cited by 11 publications

References 46 publications

Metal oxide-based composite for non-enzymatic glucose sensors

Metal oxide-based composite for non-enzymatic glucose sensors

Facile Non-Enzymatic Electrochemical Sensing for Glucose Based on Cu2O–BSA Nanoparticles Modified GCE

Review-Enzymatic and Non-Enzymatic Electrochemical Sensor for Lactate Detection in Human Biofluids

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Nano-composite of Co₃O₄and Cu with enhanced stability and catalytic performance for non-enzymatic electrochemical glucose sensors