Nano drug delivery strategy of 5-fluorouracil for the treatment of colorectal cancer

Surface-engineered nanobubbles with pH-/light-responsive drug release and charge-switchable behaviors for active NIR/MR/US imaging-guided tumor therapy

“…MGC-803 tumor-bearing mice were established by injecting 2 × 10 6 of MGC-803 cells into the right flank subcutaneously. The tumors were allowed to grow 10-14 d to reach a volume of approximately 100-200 mm 3 for in vivo or ex vivo experiments.…”

“…To enhance anticancer efficacy and reduce the adverse side effects of anticancer drugs, drug-loaded nanocarriers have been employed as an efficient medium for cancer therapy 1,2 . There are three main strategies for constructing excellent drug-loaded nanocarriers: (1) endowing nanocarriers with active cancer-targeting properties; (2) endowing visual tumor-location capacity; and (3) endowing controlled drug-release capacity in response to the tumor microenvironment or external stimulating signals [3][4][5][6][7] . Therefore, complete drug-loaded nanocarriers with enhanced tumor accumulation, integrated functions for diagnosis and therapy, efficient drug release and deep tumor penetration capacity are required.…”

A Lot of Promise for ZnO-5FU Nanoparticles Cytotoxicity against Breast Cancer Cell Lines

“…Other study includes the combination treatment of oxaliplatin and 5-fluorouracil [21]. Researchers at Lincoln University College at Malaysia present a study of Nano drug delivery strategy of 5-fluorouracil for the treatment of colorectal cancer [22]. Many other studies in the past 10 years about Nano-carrier based Drugs: The Future Promise for Treatment of Breast Cancer and Substances in the nano scale consisting of human drugs which suggested as a promising strategy for targeted drug delivery to cancer cells [23][24][25][26][27][28][29][30].…”

Solvent-free Synthesis and Characterization of MnO2 Nanostructures and Investigation of Optical Properties

“…Many reports have concerned the synthesis of NiO nanocrystals, including NiO nanorings [15], nanosheets [16], nanoribbons [17] and nanoclusters [18]. MnO 2 nanoparticles were synthesized by different methods including co-precipitation [19], microemulsion [20], sol-gel [21], sonochemical [22], hydrothermal [23] and electrochemical methods [24]. MnO 2 was the most unusual one in terms of its structural properties at ambient pressure, which are largely determined by the strong tendency for linear coordination of O-Mn-O chain geometry [25].…”