“Nano effects”: a review on nanoparticle-induced multifarious systemic effects on cancer theranostic applications

Ravichandran, Gaythri; Yadav, Dokkari Nagalaxmi; Murugappan, Sivasubramanian; Sankaranarayanan, Sri Amruthaa; Revi, Neeraja; Rengan, Aravind Kumar

doi:10.1039/d2ma00784c

Cited by 5 publications

(1 citation statement)

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“…Their small size allows them to reach the target site directly through a pathophysiological phenomenon called the enhanced permeability and retention effect (EPR), or through the surface receptors. The advantages of these nanoparticles include increased dosage efficacy, higher bioavailability, stealth nature, and minimal side effects of the chemotherapeutic drugs owing to the targeted delivery. − …”

Section: Introductionmentioning

confidence: 99%

Advances in Peptide-Decorated Targeted Drug Delivery: Exploring Therapeutic Potential and Nanocarrier Strategies

Buddhiraju,

Yadav,

Dey

et al. 2023

ACS Appl. Bio Mater.

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Peptides are ideal biologicals for targeted drug delivery and have also been increasingly employed as theranostic tools in treating various diseases, including cancer, with minimal or no side effects. Owing to their receptor-specificity, peptidemediated drug delivery aids in targeted drug delivery with better pharmacological biodistribution. Nanostructured self-assembled peptides and peptide−drug conjugates demonstrate enhanced stability and performance and captivating biological effects in comparison with conventional peptides. Moreover, they serve as valuable tools for establishing interfaces between drug carriers and biological systems, enabling the traversal of multiple biological barriers encountered by peptide−drug conjugates on their journeys to their intended targets. Peptide-based drugs play a pivotal role in the field of medicine and hold great promise for addressing a wide range of complex diseases such as cancer and autoimmune disorders. Nanotechnology has revolutionized the fields of medicine, biomedical engineering, biotechnology, and engineering sciences over the past two decades. With the help of nanotechnology, better delivery of peptides to the target site could be achieved by exploiting the small size, increased surface area, and passive targeting ability of the nanocarrier. Furthermore, nanocarriers also ensure safe delivery of the peptide moieties to the target site, protecting them from degradation. Nanobased peptide delivery systems would be of significant importance in the near future for the successful targeted and efficient delivery of peptides. This review focuses on peptide−drug conjugates and nanoparticle-mediated self-assembled peptide delivery systems in cancer therapeutics.

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Section: Introductionmentioning

confidence: 99%

Advances in Peptide-Decorated Targeted Drug Delivery: Exploring Therapeutic Potential and Nanocarrier Strategies

Buddhiraju,

Yadav,

Dey

et al. 2023

ACS Appl. Bio Mater.

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Persistent Photoinduced Antibacterial Activity of MoS₂ Nanosheets Immobilized in Porous Polymer Beads

Park,

Kim,

Shin

et al. 2024

ACS Appl. Mater. Interfaces

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Diatom-derived extracellular polymeric substances form eco-corona and enhance stability of silver nanoparticles

Gasco,

Worms,

Kantarciyan

et al. 2024

Environ. Sci.: Nano

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“Nano effects”: a review on nanoparticle-induced multifarious systemic effects on cancer theranostic applications

Abstract: The advent of nanotechnology has broadened the scope of technological advances in both medical and industrial applications. Nanotechnology had paved the way to cancer diagnosis and therapy with the conceptual...

Cited by 5 publications

References 112 publications

Advances in Peptide-Decorated Targeted Drug Delivery: Exploring Therapeutic Potential and Nanocarrier Strategies

Advances in Peptide-Decorated Targeted Drug Delivery: Exploring Therapeutic Potential and Nanocarrier Strategies

Persistent Photoinduced Antibacterial Activity of MoS₂ Nanosheets Immobilized in Porous Polymer Beads

Diatom-derived extracellular polymeric substances form eco-corona and enhance stability of silver nanoparticles

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“Nano effects”: a review on nanoparticle-induced multifarious systemic effects on cancer theranostic applications

Abstract: The advent of nanotechnology has broadened the scope of technological advances in both medical and industrial applications. Nanotechnology had paved the way to cancer diagnosis and therapy with the conceptual...

Cited by 5 publications

References 112 publications

Advances in Peptide-Decorated Targeted Drug Delivery: Exploring Therapeutic Potential and Nanocarrier Strategies

Advances in Peptide-Decorated Targeted Drug Delivery: Exploring Therapeutic Potential and Nanocarrier Strategies

Persistent Photoinduced Antibacterial Activity of MoS2 Nanosheets Immobilized in Porous Polymer Beads

Diatom-derived extracellular polymeric substances form eco-corona and enhance stability of silver nanoparticles

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Product

Resources

About

Persistent Photoinduced Antibacterial Activity of MoS₂ Nanosheets Immobilized in Porous Polymer Beads