Nano‐hydroxyapatite and nano‐hydroxyapatite/zinc oxide scaffold for bone tissue engineering application

Heidari, Fatemeh; Bazargan‐Lari, Reza; Razavi, Mehdi; Fahimipour, Farahnaz; Vashaee, Daryoosh; Tayebi, Lobat

doi:10.1111/ijac.13596

Cited by 29 publications

(8 citation statements)

References 43 publications

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“…The behavior of crack propagation and its rate in Ecoflex elastomers is distinct from that of other solid materials such as fiber-reinforced polymers [ 23 , 24 , 25 , 26 , 27 , 28 ] and other materials [ 29 , 30 ]. In most cases mentioned earlier, crack initiation begins from the designated notch position and travels parallel to it.…”

Section: Methodsmentioning

confidence: 99%

A Multiaxial Fracture of Ecoflex Skin with Different Shore Hardness for Morphing Wing Application

Ahmad

Ajaj

2023

Polymers

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The use of elastomer-based skins in morphing wings has become increasingly popular due to their remarkable stretchability and mechanical properties. However, the possibility of the skin fracturing during multiaxial stretching remains a significant design challenge. The propagation of cracks originating from flaws or notches in the skin can lead to the specimen breaking into two parts. This paper presents an experimental study aimed at comprehensively evaluating crack propagation direction, stretchability, and fracture toughness of silicone-based elastomeric skin (Ecoflex) for morphing wing applications, using varying Shore hardness values (10, 30, and 50). The findings show that the lower Shore hardness value of 10 exhibits a unique Sideways crack propagation characteristic, which is ideal for morphing skins due to its high stretchability, low actuation load, and high fracture toughness. The study also reveals that the Ecoflex 10 is suitable for use in span morphing, with a fracture toughness of approximately 1.1 kJ/m2 for all thicknesses at a slower strain rate of 0.4 mm/min. Overall, this work highlights the superior properties of Ecoflex 10 and its potential use as a morphing skin material, offering a groundbreaking solution to the challenges faced in this field.

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Section: Methodsmentioning

confidence: 99%

A Multiaxial Fracture of Ecoflex Skin with Different Shore Hardness for Morphing Wing Application

Ahmad

Ajaj

2023

Polymers

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“…The nano-hydroxyapatite/ZnO and PCL/ZnO showed bone tissue regeneration. 215 These scaffolds showed excellent and greater biocompatibility and biomineralization provided with the nano-porous matrix for the attachment and proliferation of cells.…”

Section: Mechanisms and Various Biomedical Applications Of Zno Thin F...mentioning

confidence: 99%

ZnO based 0–3D diverse nano-architectures, films and coatings for biomedical applications

Krishna,

Jakmunee,

Mishra

et al. 2024

J. Mater. Chem. B

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“…It was confidently expected that this exploration would advance tissue culture technology by increasing the rate of plant in vitro regeneration in various species. Heidari et al [ 209 ] and Harikrishnan and Sivasamy [ 210 ] reported the efficacy of nanohydroxyapatite/ZnO (HA/ZnO) scaffolds and polycaprolactone/ZnO(PCL-ZnO) scaffolds for bone tissue regeneration in human osteoblast cells. Improved biocompatibility and biosorption properties were demonstrated by the HA/ZnO scaffold, whereas PCL/ZnO scaffolds offer a nano-porous matrix for improved cell adherence and higher cell proliferation.…”

Section: Application Of Znonps In Tissue Engineeringmentioning

confidence: 99%

Recent advances in the synthesis, characterization and biomedical applications of zinc oxide nanoparticles

Asif

Amir

Fatma

2023

Bioprocess Biosyst Eng

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Zinc oxide nanoparticles (ZnONPs) have become the widely used metal oxide nanoparticles and drawn the interest of global researchers due to their biocompatibility, low toxicity, sustainability and cost-effective properties. Due to their unique optical and chemical properties, it emerges as a potential candidate in the fields of optical, electrical, food packaging and biomedical applications. Biological methods using green or natural routes are more environmentally friendly, simple and less use of hazardous techniques than chemical and/or physical methods in the long run. In addition, ZnONPs are less harmful and biodegradable while having the ability to greatly boost pharmacophore bioactivity. They play an important role in cell apoptosis because they enhance the generation of reactive oxygen species (ROS) and release zinc ions (Zn 2+ ), causing cell death. Furthermore, these ZnONPs work well in conjunction with components that aid in wound healing and biosensing to track minute amounts of biomarkers connected to a variety of illnesses. Overall, the present review discusses the synthesis and most recent developments of ZnONPs from green sources including leaves, stems, bark, roots, fruits, flowers, bacteria, fungi, algae and protein, as well as put lights on their biomedical applications such as antimicrobial, antioxidant, antidiabetic, anticancer, anti-inflammatory, antiviral, wound healing, and drug delivery, and modes of action associated. Finally, the future perspectives of biosynthesized ZnONPs in research and biomedical applications are discussed. Graphical abstract

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Nano‐hydroxyapatite and nano‐hydroxyapatite/zinc oxide scaffold for bone tissue engineering application

Cited by 29 publications

References 43 publications

A Multiaxial Fracture of Ecoflex Skin with Different Shore Hardness for Morphing Wing Application

A Multiaxial Fracture of Ecoflex Skin with Different Shore Hardness for Morphing Wing Application

ZnO based 0–3D diverse nano-architectures, films and coatings for biomedical applications

Recent advances in the synthesis, characterization and biomedical applications of zinc oxide nanoparticles

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