Nano/micro implant debris affect osteogenesis by chondrocytes: Comparison between ceramic and UHMWPE from hip walking simulator

Ben, Braham, Marwa; Trunfio-Sfarghiu, Ana-Maria; Brizuela, Leyre; Mébarek, Saida; Essefi, Ines; Géringer, Jean; Berthier, Yves; Hamza, Samir

doi:10.1002/jbm.b.34910

Cited by 1 publication

(2 citation statements)

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“…1,2 However, cases of prosthesis failure due to in vivo loosening after THA are common, 3 and current studies suggest that wear particles from the relative motion of the femoral head to the acetabulum are the main cause of loosening failure. [4][5][6] Currently, artificial acetabulums are usually made of ultra-high molecular weight polyethylene (UHMWPE) materials, but with the continuous development of materials in recent years, highly cross-linked polyethylene (XLPE) has been produced and put into clinical application in order to improve the wear resistance of UHMWPE, and at the same time, high cross-linked polyethylene doped with vitamin E (VE-XLPE) has gradually gained widespread attention in order to improve the problem of insufficient oxidation resistance of XLPE. 7,8 Taddei et al 9 compared the wear resistance of three polymers, UHMWPE, XLPE, and VE-XLPE, using a hip simulator, and found that VE-XLPE acetabulums exhibited better wear resistance properties only under long-term or more severe test conditions.…”

Section: Introductionmentioning

confidence: 99%

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Effect of synovial fluid temperature on wear resistance of different polymer acetabular materials

Wang

Lin

et al. 2023

J Biomater Appl

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In order to investigate the effect of frictional heat on the wear resistance characteristics of polymeric acetabular materials, the tribological tests and wear numerical analysis of three common polymer acetabular materials were carried out under different synovial fluid temperatures. The study results show that XLPE and VE-XLPE exhibit superior wear resistance compared to UHMWPE in high-temperature, heavy load environments. The coefficient of friction of three materials gradually decreases as the temperature of the synovial fluid increases. The wear depth and wear volume of the three materials increased with the increase of the temperature of the synovial fluid, and the forms of wear at 46°C and 55°C were mainly adhesive wear and plastic deformation. The higher temperature of the synovial fluid accelerates the oxidative degradation of the material surface and generates oxidation functional groups, which leads to the breakage of C-C bonds in the surface molecular chains under the sliding shear effect, thus reducing the mechanical properties of the material. Specifically, the surface of the polymer material will soften at a higher ambient temperature, mainly due to the decrease of hardness, and then deteriorate in the friction property, and finally increase the wear rate. Ansys results showed that the volume wear of the three materials increased with the increase of synovial fluid temperature, and the trend could be approximately linear. Numerical calculations predict that VE-XLPE has the highest wear of 0.693 mm3 among the three materials at 37°C, followed by XLPE at 0.568 mm3 and UHMWPE with the lowest wear of 0.478 mm3. At higher synovial fluid temperatures (46°C, 55°C), VE-XLPE still has the largest wear volume among the three materials, while XLPE and UHMWPE have similar wear. The wear cloud pictures showed that the maximum wear volume occurred near the edge of the acetabulum.

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