Nano/micro-scaled materials based optical biosensing of glucose

Kumar, Rajesh; Chauhan, Sandeep

doi:10.1016/j.ceramint.2021.10.170

Cited by 15 publications

(4 citation statements)

References 260 publications

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“…Optical methods for sensing glucose have been extensively studied and developed, such as colorimetry, FL, CL, SERS, etc. The optical glucose sensors based on MOF-based materials provide a visualized and cost-effective way to measure glucose concentrations compared to electrochemical glucose sensors that need relatively expensive and complicated instruments, as well as being prone to interferences [152]. However, the long-term stability and reusability of MOF-based optical glucose sensors are the major challenges for future applications.…”

Section: Optical Methodsmentioning

confidence: 99%

MOF-Based Materials for Glucose Detection

et al. 2023

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Metal–organic frameworks (MOFs), constructed by coordination between metal-containing nodes and organic linkers, are widely used in various fields due to the advantages of tunable pores, diverse functional sites, stable structure, and multi-functionality. It should be noted that MOF-based materials play a major role in glucose detection, serving as a signal transducer or functional substrate for embedding nanoparticles/enzymes. Diabetes is one of the most common and fast-growing diseases worldwide, whose main clinical manifestation is high blood sugar levels. Therefore, accurate, sensitive, and point-of-care glucose detection is necessary. This review orderly introduces general synthetic strategies of MOF-based materials (pristine MOF, nanoparticles, or enzymes-modified MOF and MOF-derived materials) and detection methods (electrochemical and optical methods) for glucose detection. Then, the review refers to the novel MOF-based glucose detection devices (flexible wearable devices and microfluidic chips), which enable non-invasive continuous glucose monitoring or low-cost microscale detection. On the basis of describing the development of glucose sensors based on MOF materials in the past five years, the review presents merits, demerits, and possible improvements of various detection methods.

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Section: Optical Methodsmentioning

confidence: 99%

MOF-Based Materials for Glucose Detection

et al. 2023

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“…The applications of TMB in colorimetric glucose sensing have been reviewed in detail elsewhere. [ 145 ] A linear range of 10–350 × 10 −6 m and LOD of 6.52 × 10 −6 m was achieved for PB@ Ti 3 C 2 T x composites.…”

Section: Optical Glucose Biosensing Applications Of Mxene Based Mater...mentioning

confidence: 99%

“…Further, it has been a verified fact that H 2 O 2 is formed as one of the important byproducts along with gluconolactone if the electrochemical sensing of the glucose is carried out in the presence of O 2 . [46][47][48] Despite its high sensitivity, enzymatic glucose sensing has some significant drawbacks. GOx is easily influenced by environmental factors like pH, temperature, and humidity.…”

Section: Electrochemical Glucose Biosensing Applications-challenges A...mentioning

confidence: 99%

Ti₃C₂T_x MXene as Electrocatalyst for Designing Robust Glucose Biosensors

Kumar¹,

Singh

2022

Adv Materials Technologies

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“…In particular, as diabetes is a worldwide public health problem, to the ability to examine the blood glucose level is of great importance. Various approaches to blood glucose testing have been reported including electrochemical methods ( Comba et al, 2018 ; Gopal et al, 2022 ; Thapa and Heo, 2023 ; Wang et al, 2023 ), optical methods ( Ramon-Marquez et al, 2017 ; Kumar and Chauhan, 2022 ; Zhenglan et al, 2022 ), and surface plasmon resonance (SPR) spectroscopy ( Man et al, 2022 ; Zhang et al, 2022 ; Zheng et al, 2022 ). Although widely applied in commercial glucose tests, electrochemical sensors have easily interfered with biological molecules such as ascorbate ( Mani et al, 2015 ).…”

Section: Introductionmentioning

confidence: 99%

Glucose determination in human serum by applying inner filter effect quenching mechanism of upconversion nanoparticles

Chen¹,

Yang²,

Chen³

et al. 2023

Front. Bioeng. Biotechnol.

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Accurate blood glucose determination is essential to the clinical diagnosis and management of diabetes. This work establishes an inner filter effect (IFE) strategy between upconversion nanoparticles (UCNPs) and quinone-imine complex for glucose monitoring in human serum simply and efficiently. In this system, the enzyme glucose oxidase (GOx) catalyzes the reaction of glucose into hydrogen peroxide (H2O2) and gluconic acid when compulsion by oxygen. In the presence of horseradish peroxidase (HRP), the produced H2O2 can catalytically oxidize phenol and 4-amino antipyrine (4-AAP) to generate quinone-imine products. The purple-colored quinone-imine complex effectively absorbed the fluorescence of NaYF4:Yb3+, Er3+ UCNPs, leading to the strong fluorescence quenching of UCNPs through IFE. Thus, a new approach was established for glucose monitoring by determining the fluorescence intensity. Under the optimal condition, this approach shows better linearity to glucose from 2–240 μmol/L with a low detection limit at 1.0 μmol/L. Owing to the excellent fluorescence property and background-free interference of the UCNPs, the biosensor was applied for glucose measurements in human serum and got a satisfactory result. Furthermore, this sensitive and selective biosensor revealed great potential for the quantitative analysis of blood glucose or different kinds of H2O2-involved biomolecules for the application of clinical diagnosis.

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Nano/micro-scaled materials based optical biosensing of glucose

Cited by 15 publications

References 260 publications

MOF-Based Materials for Glucose Detection

MOF-Based Materials for Glucose Detection

Ti₃C₂T_x MXene as Electrocatalyst for Designing Robust Glucose Biosensors

Glucose determination in human serum by applying inner filter effect quenching mechanism of upconversion nanoparticles

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Nano/micro-scaled materials based optical biosensing of glucose

Cited by 15 publications

References 260 publications

MOF-Based Materials for Glucose Detection

MOF-Based Materials for Glucose Detection

Ti3C2Tx MXene as Electrocatalyst for Designing Robust Glucose Biosensors

Glucose determination in human serum by applying inner filter effect quenching mechanism of upconversion nanoparticles

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Ti₃C₂T_x MXene as Electrocatalyst for Designing Robust Glucose Biosensors