Nano-Nutraceuticals for Health: Principles and Applications

Magne, Tais Monteiro; Alencar, Luciana Magalhães Rebêlo; Carneiro, Samuel Veloso; Fechine, Lillian Maria Uchôa Dutra; Fechine, Pierre Basílio Almeida; Santos-Oliveira, Ralph; Portilho, Filipe Leal; Barros, Aline Oliveira da Silva de; Johari, Seyed Ali; Ricci, Esther Lopes

doi:10.1007/s43450-022-00338-7

Cited by 8 publications

(4 citation statements)

References 146 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A good example is Sinocurcumin. Curcumin is well‐known for its antiviral properties; however, it has limited clinical usage due to its low stability and solubility, rapid metabolism, high renal clearance rate, and poor bioavailability (Magne et al, 2023). However, a nano‐formulated curcumin, known as sinocarcumin demonstrated great improvement, in terms of its stability, solubility, bioavailability, and controlled dissociation rate, thus enhancing overall PK in vivo.…”

Section: Nano‐formulated Supplementsmentioning

confidence: 99%

Role of dietary supplements in the continuous battle against COVID‐19

Zaman,

Ravichandran,

Tan

2024

Phytotherapy Research

View full text Add to dashboard Cite

A sudden outbreak of the COVID‐19 pandemic was a big blow to the world community on every level. Created by a novel coronavirus, SARS‐CoV‐2, which was previously unknown to the human immune system. The expert opinion almost immediately united on the fact that the most effective way of fighting the pandemic would be by building immunity artificially via a mass immunization program. However, it took about a year for the approval of the first vaccine against COVID‐19. In the meantime, a big part of the general population started adapting nutritious diet plans and dietary supplements to boost natural immunity as a potential prophylactic strategy against SARS‐CoV‐2 infection. Whether they originate from mainstream medicine, such as synthetic supplements, or traditional herbal remedies in the form of single or poly‐herbs, these supplements may comprise various components that exhibit immunomodulatory, anti‐inflammatory, antioxidant, and antimicrobial characteristics. There is a substantial body of predictions and expert opinions suggesting that enhancing one's diet with dietary supplements containing additional nutrients and bioactive compounds like vitamins, minerals, amino acids, fatty acids, phytochemicals, and probiotics can enhance the immune system's ability to develop resistance against COVID‐19, although none of them have any conclusive evidence nor officially recommended by World Health Organization (WHO). The current review critically acclaims the gap between public perception‐based preference and real evidence‐based study to weigh the actual benefit of dietary supplements in relation to COVID‐19 prevention and management.

show abstract

Section: Nano‐formulated Supplementsmentioning

confidence: 99%

Role of dietary supplements in the continuous battle against COVID‐19

Zaman,

Ravichandran,

Tan

2024

Phytotherapy Research

View full text Add to dashboard Cite

show abstract

“…Microencapsulation helps protect probiotics from harsh stomach conditions, ensuring their survival and efficacy in the digestive system. [427][428][429][430][431][432][433] Drug delivery systems in cosmetics involve the encapsulation of active ingredients in nanocarriers like liposomes or nanoparticles. This ensures controlled release, targeted delivery, and enhanced penetration of substances into the skin for improved efficacy.…”

Section: Application -Therapy Diagnostic Imaging Cosmetics Nutraceuti...mentioning

confidence: 99%

Nanoscale materials at work: Mapping emerging applications in energy, medicine, and beyond

Hughes,

Ganesan,

Tenchov

et al. 2024

Preprint

View full text Add to dashboard Cite

Since their inception in the early 1960s, the use of nanoscale materials has progressed in leaps and bounds, and their role in diverse fields ranging from human health to energy is undeniable. In this report, we utilize the CAS Content Collection, a vast repository of scientific information extracted from journal and patent publications, to identify emerging topics in this field. This involves understanding trends, such as the growth of certain topics over time, as well as establishing relationships between emerging topics. We achieved this by using a host of strategies including a quantitative natural language processing (NLP) approach to identify 279 emerging topics and sub-topics across three major categories – materials, applications, and properties – by surveying roughly 3 million publications in the nanoscience landscape. This wealth of information has been condensed into several conceptual mind maps and other graphs that provide metrics related to the growth of identified emerging concepts, group them into hierarchical classes, and explore the connections between them. We delved deeper into four major emerging applications of nanoscale materials – drug delivery, sensors, energy, and catalysis – to provide a more comprehensive and detailed picture of the use of nanotechnology in these fields. In addition, we leveraged the CAS registry, consisting of over 250 million substances, to determine and discover substances across varied classes (such as polymers, elements, organic/inorganic molecules) and how they are utilized in the 4 major applications. Our extensive analysis taking advantage of an NLP-based approach along with robust CAS indexing provides valuable insights in the field that we hope can help to inform and drive future research efforts.

show abstract

“…The integration of nanotechnology in nutraceuticals for cancer treatment has a significant potential for improving patient outcomes. Applications of nano nutraceuticals in anticancer therapy include targeted drug delivery, enhanced bioavailability, increased solubility, improved stability, and mitigation of unfavorable side effects (225)(226)(227). Phytoconstituents such as curcumin, quercetin, and resveratrol are becoming more effective in cancer treatment due to nanotechnology advancements that allow for better absorption and therapeutic efficacy.…”

Section: Applications Of Nano Nutraceuticals In Anticancer Therapymentioning

confidence: 99%

Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment

Singla,

Smriti,

Gupta

et al. 2023

Front. Nutr.

View full text Add to dashboard Cite

Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled proliferation of cells that can lead to serious health complications and ultimately death. Conventional therapeutic strategies mainly target rapidly dividing cancer cells, but often indiscriminately harm healthy cells in the process. As a result, there is a growing interest in exploring novel therapies that are both effective and less toxic to normal cells. Herbs have long been used as natural remedies for various diseases and conditions. Some herbal compounds exhibit potent anti-cancer properties, making them potential candidates for nutraceutical-based treatments. However, despite their promising efficacy, there are considerable limitations in utilizing herbal preparations due to their poor solubility, low bioavailability, rapid metabolism and excretion, as well as potential interference with other medications. Nanotechnology offers a unique platform to overcome these challenges by encapsulating herbal compounds within nanoparticles. This approach not only increases solubility and stability but also enhances the cellular uptake of nutraceuticals, allowing for controlled and targeted delivery of therapeutic agents directly at tumor sites. By harnessing the power of nanotechnology-enabled therapy, this new frontier in cancer treatment presents an opportunity to minimize toxicity while maximizing efficacy. In conclusion, this manuscript provides compelling evidence for integrating nanotechnology with nutraceuticals derived from herbal sources to optimize cancer therapy outcomes. We explore the roadblocks associated with traditional herbal treatments and demonstrate how nanotechnology can help circumvent these issues, paving the way for safer and more effective cancer interventions in future oncological practice.

show abstract

Nano-Nutraceuticals for Health: Principles and Applications

Cited by 8 publications

References 146 publications

Role of dietary supplements in the continuous battle against COVID‐19

Role of dietary supplements in the continuous battle against COVID‐19

Nanoscale materials at work: Mapping emerging applications in energy, medicine, and beyond

Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment

Contact Info

Product

Resources

About