Nano-sized NiLa2O4 spinel–NaBH4-mediated reduction of imines to secondary amines

Process Intensification of Continuous-Flow Imine Hydrogenation in Catalyst-Coated Tube Reactors

“…[29][30][31] Imines subsequently can be hydrogenated to amines via transfer hydrogenation or by molecular hydrogen over homogeneous or heterogeneous catalysts. [32][33][34][35] The possibility of using flow chemistry for imine reduction has been already noted in a previous research. 36 However, the vast majority of the modern research on secondary amine synthesis is carried out in batch reactors and the advantages of continuous-flow might be overlooked.…”

“…Their synthesis commonly includes a primary amine alkylation or imine hydrogenation. , Alkylation involves application of potentially carcinogenic alkyl halides, while imine hydrogenation stands out as a better alternative with excellent yields and atom economy. Imines, in turn, can be obtained using simple procedures of ketone or aldehyde amination, − alkylation of amines and aryls, , or hydrogenation of nitriles. − Imines subsequently can be hydrogenated to amines via transfer hydrogenation or by molecular hydrogen over homogeneous or heterogeneous catalysts. − …”

Photo- and electro-catalytic deuteration of feedstock chemicals and pharmaceuticals: A review

“…(2) Mild and precise substitution of deuterium at the metabolic positions of drugs to improve their biological activities. For example, amine is a core structural motif found in many medicinal agents and bioactive alkaloids [93][94][95][96]. In fact, N-α-dehydrogenation metabolized cytochrome P450 is commonly found in N-containing drugs and other bioactive molecules.…”

Syngas Production via Methane Dry Reforming over La-Ni-Co and La-Ni-Cu Catalysts with Spinel and Perovskite Structures

“…Non substituted La-Ni and substituted La-Ni-M (M = Co, Cu) with spinel and perovskite structures were prepared by the sol-gel method using nitrates salts and citric acid as raw materials [24]. The non substituted samples are perovskite LaNiO3 (noted LN3) and spinel La2NiO4 (noted LN4).…”