2024
DOI: 10.1007/s00210-024-03483-z
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Nano Spirulina platensis countered cisplatin-induced repro-toxicity by reversing the expression of altered steroid hormones and downregulation of the StAR gene

Eman M. Khalil,
Mohamed I. Rady,
Samah F. Darwish
et al.

Abstract: Cisplatin is a commonly utilized chemotherapy medication for treating different sarcomas and carcinomas. Its ability interferes with cancer cells’ DNA repair pathways and postpones unfavorable outcomes in cancer patients. The current investigation’s goal was to ascertain if nano Spirulina platensis (NSP) might shield rat testicles from cisplatin damage by assessing the expression of the StAR and SOD genes, sex hormones, 17ß-hydroxysteroid dehydrogenase(17ß-HSD), sperm profile picture, oxidative condition of te… Show more

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