The paper delves into various aspects of nanotechnology in mechanical engineering, including the fabrication of nanomaterials and advanced manufacturing techniques. Nanomanufacturing methods offer unprecedented precision and control, enhancing efficiency and performance across industries. From nanoscale manipulation to intricate structure fabrication, nanotechnology is transforming manufacturing processes profoundly. Furthermore, the paper explores the applications of nanotechnology in nano mechanics and nanotribology, elucidating how it enables us to understand and manipulate mechanical behaviours at the nanoscale. Additionally, it discusses the role of nanotechnology in energy systems, where nanomaterials contribute to improved energy storage and conversion efficiency. Beyond traditional mechanical engineering, nanotechnology finds applications in biomechanics, shaping advancements in healthcare through innovative biomedical devices and materials. The interdisciplinary nature of nanotechnology is evident in its potential to address global challenges, such as environmental remediation, by developing nanomaterials for water purification, air filtration, and soil remediation. Looking ahead, the paper discusses future directions for nanotechnology in mechanical engineering, emphasizing the importance of interdisciplinary collaboration, ethical considerations, and responsible governance. It highlights the potential for transformative breakthroughs in medicine, energy systems, and materials science, guided by ongoing research and innovation. In conclusion, nanotechnology is poised to reshape the landscape of mechanical engineering, offering unprecedented possibilities for efficiency, sustainability, and technological advancement. Through careful exploration and application, nanotechnology holds the promise of addressing societal needs while pushing the boundaries of what is possible in mechanical engineering.