Nanobiosensing with graphene and carbon quantum dots: Recent advances

Walther, Brandon K.; Dinu, Cerasela Zoica; Guldi, Dirk M.; Sergeyev, Vladimir G.; Creager, Stephen E.; Cooke, John P.; Guiseppi‐Elie, Anthony

doi:10.1016/j.mattod.2020.04.008

Cited by 84 publications

(44 citation statements)

References 226 publications

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“…They are also crucial to proceed surface passivation. Nanodots can be doped by heteroatoms or grafted with various compounds to increase quantum yield or affinity to certain biomolecules, which make them an ideal candidate for the most advanced and sensitive tools for biosensing and bioimaging [ 30 , 31 , 32 , 33 , 34 , 35 ]. Additionally, they exhibit excellent stability in aqueous media.…”

Section: Introductionmentioning

confidence: 99%

Facile Synthesis of Surface-Modified Carbon Quantum Dots (CQDs) for Biosensing and Bioimaging

et al. 2020

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Recently, fluorescent probes became one of the most efficient tools for biosensing and bioimaging. Special attention is focused on carbon quantum dots (CQDs), which are characterized by the water solubility and lack of cytotoxicity. Moreover, they exhibit higher photostability comparing to traditional organic dyes. Currently, there is a great need for the novel, luminescent nanomaterials with tunable properties enabling fast and effective analysis of the biological samples. In this article, we propose a new, ecofriendly bottom-up synthesis approach for intelligent, surface-modified nanodots preparation using bioproducts as a raw material. Obtained nanomaterials were characterized over their morphology, chemical structure and switchable luminescence. Their possible use as a nanodevice for medicine was investigated. Finally, the products were confirmed to be non-toxic to fibroblasts and capable of cell imaging.

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Section: Introductionmentioning

confidence: 99%

Facile Synthesis of Surface-Modified Carbon Quantum Dots (CQDs) for Biosensing and Bioimaging

et al. 2020

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“…These can be classified as conformation-changing, redox reaction and binding-only molecules. : [32] Binding-only molecules -Figure 1 (MIP) and antibodies, to which the target analyte binds. This binding can be detected, often through the corresponding increased steric blocking of redox active species to the electrode.…”

Section: Biorecognition Elementsmodificationsmentioning

confidence: 99%

Electrochemical biosensors: a nexus for precision medicine

Pollard

Ong

Goyanes

et al. 2021

Drug Discovery Today

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“…Quantum dots (QDs) are semiconducting nanoparticles with a particle size in the nanometer range. [125] The unique optical characteristics of QDs, as well as their fascinating physical and chemical properties, have led to entirely new avenues for biomedical applications. Boriachek et al reported an EV quantitation method that used QDs as the indicator.…”

Section: Fluorescence Biosensorsmentioning

confidence: 99%

Extracellular Vesicles for the Diagnosis of Cancers

Xue

Fan

et al. 2021

Small Structures

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Extracellular vesicles (EVs) are ultrasmall structures secreted by various types of cells and carry biomarkers such as DNA, RNA, and the protein of the cells that secreted them. Cancer cell-derived EVs can be detected at the very early stage of cancers, and hence the use of EVs for cancer diagnosis has aroused significant interest. This review summarizes the representative strategies of using EVs as biomarkers to detect different types of cancers, evaluates their advantages and challenges, and discusses their development prospects for cancer early diagnosis.

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Nanobiosensing with graphene and carbon quantum dots: Recent advances

Cited by 84 publications

References 226 publications

Facile Synthesis of Surface-Modified Carbon Quantum Dots (CQDs) for Biosensing and Bioimaging

Facile Synthesis of Surface-Modified Carbon Quantum Dots (CQDs) for Biosensing and Bioimaging

Electrochemical biosensors: a nexus for precision medicine

Extracellular Vesicles for the Diagnosis of Cancers

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